{"type":"trials","record":{"id":87160,"source_id":"isrctn","external_id":"ISRCTN25867083","title":"Egg Xanthophyll Interventional Trial","brief_summary":"The aim of this study is to measure serum, macular and cognitive responses to supplementation with lutein (L), zeaxanthin (Z) and meso-Z (MZ) fortified eggs.","overall_status":"Completed","phases":["Not Applicable"],"study_type":"Interventional","sponsor":"The Howard Foundation (UK)","enrollment":50,"countries":["Ireland"],"start_date":"2013-09-16","completion_date":"2013-11-30","last_update_date":"2013-08-09","source_url":"https://www.isrctn.com/ISRCTN25867083","editorial_summary":"A registered Not Applicable study indexed because it matched monitored longevity research terms. Registry status: Completed. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T03:46:39.792962+00:00","last_seen_at":"2026-09-25T03:46:39.551+00:00","metadata":{"sex":"All","age_range":"Adult","comparator":null,"attribution":"Source: ISRCTN ISRCTN25867083; retrieved 2026-09-25","interventions":["Other"],"reuse_license":"Registry contribution CC BY 4.0; generated metadata CC0","registry_source":"ISRCTN","outcome_measures":["Macular pigment response: measured using the Spectralis OCT (Heidelberg Engineering); cognitive function is measured us…","Serum carotenoid response: measured using high performance liquid chromatography (HPLC)"],"design_description":"Interventional","source_has_results":false},"controlled_terms":["Age-related macular degeneration","Volunteers will be provided with eggs containing different amounts of the macular pigments, or a normal non-enriched eg…","Other"],"relevance_confidence":60,"source_quality_score":98,"freshness_score":35,"publication_state":"published","match_explanation":"Source terminology contains: age-related macular degeneration.","quality_checked_at":"2026-09-25T03:46:42.633202+00:00","duplicate_cluster_key":"id:isrctn25867083","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2013-09-16 to 2013-11-30","comparator":null,"confidence":"structured-source","population":"All · Adult","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T03:46:39.585Z","intervention":["Other"],"participants":50,"study_design":"Interventional","subject_scope":"Human clinical study registration","evidence_stage":"Not Applicable","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["Macular pigment response: measured using the Spectralis OCT (Heidelberg Engineering); cognitive function is measured us…","Serum carotenoid response: measured using high performance liquid chromatography (HPLC)"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"vision-aging","is_published":true,"match_reasons":["Source terminology contains: age-related macular degeneration.","Source terminology supplies longevity context: age-related.","Study type is explicitly identified as Interventional."],"matched_fields":["controlled terminology","controlled context","study type"],"relevance_score":60,"intelligence_topics":{"name":"Vision ageing","slug":"vision-aging"}}],"content_sources":{"name":"ISRCTN Registry","homepage_url":"https://www.isrctn.com/"}},"canonical_url":"https://www.immortal.life/trials/87160","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}