{"type":"trials","record":{"id":87194,"source_id":"isrctn","external_id":"ISRCTN98246501","title":"Double-masked, randomized, parallel, comparative study of oral supplementation with DecosaHexaenoic Acid (DHA) versus placebo in the prevention of age-related macular degeneration","brief_summary":"Oral supplementation of DHA is able to delay the occurrence of neovessels in the fellow eye of patients already presenting neovascular age-related macular degeneration in one eye","overall_status":"Completed","phases":[],"study_type":"Interventional","sponsor":"Laboratoire Chauvin, Bausch & Lomb Inc. (France)","enrollment":300,"countries":["France"],"start_date":"2003-12-23","completion_date":"2008-11-30","last_update_date":"2016-02-24","source_url":"https://www.isrctn.com/ISRCTN98246501","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Completed. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T03:46:39.792962+00:00","last_seen_at":"2026-09-25T03:46:39.551+00:00","metadata":{"sex":"All","age_range":"Senior","comparator":null,"attribution":"Source: ISRCTN ISRCTN98246501; retrieved 2026-09-25","interventions":["Supplement"],"reuse_license":"Registry contribution CC BY 4.0; generated metadata CC0","registry_source":"ISRCTN","outcome_measures":["Time to occurrence of choroidal new vessels in the study eye from prospective assessment of fluorescein angiography","Efficacy (in study eye): 1. Percentage of patients for whom new vessels occur during the study 2. Change from baseline…"],"design_description":"Interventional","source_has_results":false},"controlled_terms":["Macular degeneration","Intervention group: Oral supplementation with 840 mg of DHA per day (3 capsules per day [2 capsules at midday and 1 cap…","results","Supplement"],"relevance_confidence":100,"source_quality_score":98,"freshness_score":35,"publication_state":"published","match_explanation":"Title contains controlled term: age-related macular degeneration.","quality_checked_at":"2026-09-25T03:46:42.633202+00:00","duplicate_cluster_key":"id:isrctn98246501","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2003-12-23 to 2008-11-30","comparator":null,"confidence":"structured-source","population":"All · Senior","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T03:46:39.599Z","intervention":["Supplement"],"participants":300,"study_design":"Interventional","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["Time to occurrence of choroidal new vessels in the study eye from prospective assessment of fluorescein angiography","Efficacy (in study eye): 1. Percentage of patients for whom new vessels occur during the study 2. Change from baseline…"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"vision-aging","is_published":true,"match_reasons":["Title contains controlled term: age-related macular degeneration.","Abstract contains controlled term: age-related macular degeneration.","Title supplies longevity context: age-related.","Study type is explicitly identified as Interventional."],"matched_fields":["title","abstract","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Vision ageing","slug":"vision-aging"}}],"content_sources":{"name":"ISRCTN Registry","homepage_url":"https://www.isrctn.com/"}},"canonical_url":"https://www.immortal.life/trials/87194","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}