{"type":"trials","record":{"id":87196,"source_id":"isrctn","external_id":"ISRCTN57556290","title":"A multi-site trial of a novel nutritional supplement (taurine, omega-3 fatty acids, zinc, antioxidants, and lutein) and micro-current stimulation in the treatment of atrophic (dry) age-related macular degeneration","brief_summary":"1. A novel nutritional supplement containing antioxidants and omega-3 fatty acids improves visual acuity in patients with atrophic (dry) age-related macular degeneration. 2. Micro-current stimulation in combination with a novel nutritional supplement containing antioxidants and omega-3 fatty acids improves visual acuity in patients with atrophic (dry) age-related macular degeneration.","overall_status":"Completed","phases":[],"study_type":"Interventional","sponsor":"Atlantic Medical, Inc. (USA)","enrollment":80,"countries":["United States of America"],"start_date":"2004-04-01","completion_date":"2005-04-05","last_update_date":"2009-09-25","source_url":"https://www.isrctn.com/ISRCTN57556290","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Completed. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T03:46:39.792962+00:00","last_seen_at":"2026-09-25T03:46:39.551+00:00","metadata":{"sex":"Not Specified","age_range":"Senior","comparator":null,"attribution":"Source: ISRCTN ISRCTN57556290; retrieved 2026-09-25","interventions":["Nutritional supplement","Supplement"],"reuse_license":"Registry contribution CC BY 4.0; generated metadata CC0","registry_source":"ISRCTN","outcome_measures":["Measure the change in visual acuity from baseline at six months.","Measure objective signs of improved macular function."],"design_description":"Interventional","source_has_results":false},"controlled_terms":["Atrophic (dry) age-related macular degeneration","Nutritional supplement for six months consisting of vitamin A 10,000 IU, beta-carotene 18,640 IU, vitamin E 200 IU, vit…","results","Nutritional supplement","Supplement"],"relevance_confidence":100,"source_quality_score":98,"freshness_score":35,"publication_state":"published","match_explanation":"Title contains controlled term: age-related macular degeneration.","quality_checked_at":"2026-09-25T03:46:42.633202+00:00","duplicate_cluster_key":"id:isrctn57556290","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2004-04-01 to 2005-04-05","comparator":null,"confidence":"structured-source","population":"Not Specified · Senior","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T03:46:39.599Z","intervention":["Nutritional supplement","Supplement"],"participants":80,"study_design":"Interventional","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["Measure the change in visual acuity from baseline at six months.","Measure objective signs of improved macular function."],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"vision-aging","is_published":true,"match_reasons":["Title contains controlled term: age-related macular degeneration.","Abstract contains controlled term: age-related macular degeneration.","Source terminology contains: age-related macular degeneration.","Title supplies longevity context: age-related.","Study type is explicitly identified as Interventional."],"matched_fields":["title","abstract","controlled terminology","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Vision ageing","slug":"vision-aging"}}],"content_sources":{"name":"ISRCTN Registry","homepage_url":"https://www.isrctn.com/"}},"canonical_url":"https://www.immortal.life/trials/87196","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}