{"type":"trials","record":{"id":87247,"source_id":"isrctn","external_id":"ISRCTN18536057","title":"Improving the oral health of older adults using milk supplemented with fluoride and probiotics","brief_summary":"1. Milk is an efficient, acceptable, and feasible vehicle to deliver fluoride and probiotics on a community basis. 2. Milk supplemented with fluoride and probiotics is more effective than milk supplemented with either fluoride or probiotics in improving the oral health of older adults.","overall_status":"Completed","phases":[],"study_type":"Interventional","sponsor":"Teesside University","enrollment":88,"countries":["United Kingdom","England"],"start_date":"2023-03-09","completion_date":"2025-02-28","last_update_date":"2026-03-31","source_url":"https://www.isrctn.com/ISRCTN18536057","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Completed. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T03:46:46.8379+00:00","last_seen_at":"2026-09-25T03:46:46.614+00:00","metadata":{"sex":"All","age_range":"Senior","comparator":null,"attribution":"Source: ISRCTN ISRCTN18536057; retrieved 2026-09-25","interventions":["Supplement"],"reuse_license":"Registry contribution CC BY 4.0; generated metadata CC0","registry_source":"ISRCTN","outcome_measures":["Current primary outcome measure as of 18/08/2023: 1. Acceptability of the supplemented milk measured by assessing the n…","There are no secondary outcome measures"],"design_description":"Interventional","source_has_results":false},"controlled_terms":["Improve oral health of older adults living in care homes","Current intervention as of 18/08/2023: Trial intervention: The trial aims to recruit at least 240 Care Home Residents.…","Protocol file","Participant information sheet","Results article","Supplement"],"relevance_confidence":100,"source_quality_score":98,"freshness_score":100,"publication_state":"published","match_explanation":"Title contains controlled term: oral health.","quality_checked_at":"2026-09-25T03:46:48.948413+00:00","duplicate_cluster_key":"id:isrctn18536057","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2023-03-09 to 2025-02-28","comparator":null,"confidence":"structured-source","population":"All · Senior","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T03:46:46.630Z","intervention":["Supplement"],"participants":88,"study_design":"Interventional","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["Current primary outcome measure as of 18/08/2023: 1. Acceptability of the supplemented milk measured by assessing the n…","There are no secondary outcome measures"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"oral-health-aging","is_published":true,"match_reasons":["Title contains controlled term: oral health.","Abstract contains controlled term: oral health.","Source terminology contains: oral health.","Title supplies longevity context: older adult.","Study type is explicitly identified as Interventional."],"matched_fields":["title","abstract","controlled terminology","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Oral health and ageing","slug":"oral-health-aging"}}],"content_sources":{"name":"ISRCTN Registry","homepage_url":"https://www.isrctn.com/"}},"canonical_url":"https://www.immortal.life/trials/87247","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}