{"type":"trials","record":{"id":90654,"source_id":"clinicaltrials-gov","external_id":"NCT03551132","title":"Effects of Resistance Training on Physical Performance, Health and Quality of Life in Elderly (RTCHealth)","brief_summary":"Physical exercise is considered an important intervention for promoting well-being and healthy aging. The purpose of the present study was to determine the effects of moderate-to-high intensity resistance training circuit on different parameters of fat mass, functional autonomy, strength and quality of life in elderly. A randomized controlled trial was conducted. A total of 45 subjects, (27 females, 18 males) aged between 65-75 years old from Murcia (Spain) were randomly to experimental group (resistance training circuit for 12-weeks and isocaloric diet program) and control group (no resistance training intervention). Fat mass, functional autonomy, muscular strength, perceived exertion, and quality of life perception were obtained with validated tools. Experimental group decreases significantly their fat mass percentage whilst control group not presented differences. Muscular strength results exhibited significant differences between intervention training protocol. Furthermore, experimental group presented better marks than control group at quality of life questionnaire and functional autonomy scores. The moderate-to-high intensity resistance training circuit showed increase in upper and lower muscular strength as well as functional capacity and significantly decreased total fat mass and that improvements in physical function predict improvements in QoL perception in elderly.","overall_status":"Completed","phases":[],"study_type":"INTERVENTIONAL","sponsor":"Universidad Católica San Antonio de Murcia","enrollment":45,"countries":["Spain"],"start_date":"2018-05-15","completion_date":"2018-05-15","last_update_date":"2018-06-11","source_url":"https://clinicaltrials.gov/study/NCT03551132","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Completed. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T04:15:35.799123+00:00","last_seen_at":"2026-09-25T05:35:07.553+00:00","metadata":{"sex":"ALL","acronym":"RTCHealth","age_range":"65 Years to 75 Years","comparator":"Group 2","organization":"Universidad Católica San Antonio de Murcia","interventions":["Exercise test"],"registry_source":"ClinicalTrials.gov","outcome_measures":["body weight in kilograms — Change from Baseline body weight (kg) at 12 weeks","height in meters — Change from Baseline standing height (cm) at 12 weeks","Body Mass Index (BMI) — Change from Baseline Body Mass Index (BMI): (kg/m^2) at 12 weeks","% Fat mass — Change from Baseline bioelectrical impedance % fat mass at 12 weeks","Quality of life — Change from Baseline Quality of Life perception at 12 weeks","Functional autonomy — Change from Baseline Functional autonomy at 12 weeks","Muscular strength — Change from Baseline Muscular Strength at 12 weeks"],"design_description":"RANDOMIZED · PARALLEL · BASIC SCIENCE · SINGLE","source_has_results":false},"controlled_terms":["Sarcopenia","Body Weight Changes","Quality of Life","Exercise test"],"relevance_confidence":100,"source_quality_score":100,"freshness_score":50,"publication_state":"published","match_explanation":"Title contains controlled term: resistance training.","quality_checked_at":"2026-09-25T05:35:12.977559+00:00","duplicate_cluster_key":"id:nct03551132","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2018-05-15 to 2018-05-15","comparator":"Group 2","confidence":"structured-source","population":"ALL · 65 Years to 75 Years","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T05:35:07.565Z","intervention":["Exercise test"],"participants":45,"study_design":"RANDOMIZED · PARALLEL · BASIC SCIENCE · SINGLE","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["body weight in kilograms — Change from Baseline body weight (kg) at 12 weeks","height in meters — Change from Baseline standing height (cm) at 12 weeks","Body Mass Index (BMI) — Change from Baseline Body Mass Index (BMI): (kg/m^2) at 12 weeks","% Fat mass — Change from Baseline bioelectrical impedance % fat mass at 12 weeks","Quality of life — Change from Baseline Quality of Life perception at 12 weeks","Functional autonomy — Change from Baseline Functional autonomy at 12 weeks","Muscular strength — Change from Baseline Muscular Strength at 12 weeks"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"resistance-training","is_published":true,"match_reasons":["Title contains controlled term: resistance training.","Abstract contains controlled term: resistance training.","Title supplies longevity context: elderly.","Study type is explicitly identified as INTERVENTIONAL."],"matched_fields":["title","abstract","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Resistance training","slug":"resistance-training"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/90654","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}