{"type":"trials","record":{"id":90656,"source_id":"clinicaltrials-gov","external_id":"NCT03530202","title":"Effects of High-velocity Resistance Training and Creatine Supplementation in Healthy Aging Males","brief_summary":"The age-related loss of skeletal muscle mass (i.e. sarcopenia)and muscle performance (i.e. strength and power), decreases functionality and the ability to perform activities of daily living. Therefore, lifestyle interventions which may improve aging muscle health are important (i.e. resistance training and creatine supplementation). High-velocity resistance training (HVRT) has been shown to increase muscle mass and muscle performance in aging adults. Creatine (CR), a compound naturally found in red meat and seafood, has also been shown to increase muscle mass and muscle performance in aging adults. No study has examined the combined effects of HVRT and CR supplementation in aging adults. This study may determine whether this lifestyle intervention is effective to combat sarcopenia.","overall_status":"Unknown","phases":["PHASE2"],"study_type":"INTERVENTIONAL","sponsor":"University of Regina","enrollment":40,"countries":["Canada"],"start_date":"2018-01-01","completion_date":"2018-07-31","last_update_date":"2018-05-21","source_url":"https://clinicaltrials.gov/study/NCT03530202","editorial_summary":"A registered PHASE2 study indexed because it matched monitored longevity research terms. Registry status: Unknown. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T04:15:35.799123+00:00","last_seen_at":"2026-09-25T05:35:07.553+00:00","metadata":{"sex":"MALE","acronym":null,"age_range":"50 Years","comparator":"HVRT + Maltodextrin Powder","organization":"University of Regina","interventions":["Creatine monohydrate","Maltodextrin Powder"],"registry_source":"ClinicalTrials.gov","outcome_measures":["Change in muscle thickness — Baseline and again once intervention is completed (8 weeks)","Change in muscle strength — Baseline and again once intervention is completed (8 weeks)","Change in peak torque (Nm) — Baseline and again once intervention is completed (8 weeks)","Change peak muscle power (watts) — Baseline and again once intervention is completed (8 weeks)","Change in dynamic balance — Baseline and again once intervention is completed (8 weeks)","Walking speed — Baseline and again once intervention is completed (8 weeks)"],"design_description":"RANDOMIZED · PARALLEL · PREVENTION · DOUBLE","source_has_results":false},"controlled_terms":["Sarcopenia","Creatine monohydrate","Maltodextrin Powder"],"relevance_confidence":100,"source_quality_score":100,"freshness_score":50,"publication_state":"published","match_explanation":"Title contains controlled term: resistance training.","quality_checked_at":"2026-09-25T05:35:12.977559+00:00","duplicate_cluster_key":"id:nct03530202","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2018-01-01 to 2018-07-31","comparator":"HVRT + Maltodextrin Powder","confidence":"structured-source","population":"MALE · 50 Years","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T05:35:07.566Z","intervention":["Creatine monohydrate","Maltodextrin Powder"],"participants":40,"study_design":"RANDOMIZED · PARALLEL · PREVENTION · DOUBLE","subject_scope":"Human clinical study registration","evidence_stage":"PHASE2","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["Change in muscle thickness — Baseline and again once intervention is completed (8 weeks)","Change in muscle strength — Baseline and again once intervention is completed (8 weeks)","Change in peak torque (Nm) — Baseline and again once intervention is completed (8 weeks)","Change peak muscle power (watts) — Baseline and again once intervention is completed (8 weeks)","Change in dynamic balance — Baseline and again once intervention is completed (8 weeks)","Walking speed — Baseline and again once intervention is completed (8 weeks)"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"resistance-training","is_published":true,"match_reasons":["Title contains controlled term: resistance training.","Abstract contains controlled term: resistance training.","Title supplies longevity context: aging.","Study type is explicitly identified as INTERVENTIONAL."],"matched_fields":["title","abstract","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Resistance training","slug":"resistance-training"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/90656","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}