{"type":"trials","record":{"id":90706,"source_id":"clinicaltrials-gov","external_id":"NCT02582138","title":"Multicomponent Intervention for Physical Frailty and Sarcopenia","brief_summary":"The SPRINTT study will evaluate the efficacy of a multicomponent intervention programme (physical activity, nutritional counselling/dietary intervention, and information and communications technology intervention) compared with a healthy aging lifestyle education programme on mobility disability, in non-disabled older people with physical frailty and sarcopenia.","overall_status":"Unknown","phases":[],"study_type":"INTERVENTIONAL","sponsor":"Catholic University of the Sacred Heart","enrollment":1500,"countries":["Italy"],"start_date":"2016-01-01","completion_date":"2018-12-01","last_update_date":"2017-02-02","source_url":"https://clinicaltrials.gov/study/NCT02582138","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Unknown. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T04:15:35.799123+00:00","last_seen_at":"2026-09-25T04:15:35.417+00:00","metadata":{"sex":"ALL","acronym":"SPRINTT","age_range":"70 Years","comparator":"Healthy Aging Lifestyle Education (HALE)","organization":"Catholic University of the Sacred Heart","interventions":["Multicomponent intervention (MCI)","Healthy Aging Lifestyle Education (HALE)"],"registry_source":"ClinicalTrials.gov","outcome_measures":["Incident of major mobility disability — 36 months","Changes in lower extremity physical performance — 36 months","Changes in upper extremity muscle strength — 36 months","Changes in functional status (activities of daily living) — 36 months","Changes in functional status (instrumental activities of daily living) — 36 months","Changes in crude appendicular lean mass — 36 months","Changes in body mass index-adjusted appendicular lean mass — 36 months","Persistent mobility disability — 36 months","Changes in body weight — 36 months","Changes in body mass index — 36 months","Changes in mid-arm circumference — 36 months","Changes in waist circumference — 36 months","Changes in hip circumference — 36 months","Changes in calf circumference — 36 months","Changes in nutritional status — 36 months","Changes in cognitive function — 36 months","Changes in mood — 36 months","Incidence of self-reported falls — 36 months","Incidence of injurious falls — 36 months","Changes in quality of life — 36 months"],"design_description":"RANDOMIZED · PARALLEL · PREVENTION · SINGLE","source_has_results":false},"controlled_terms":["Sarcopenia","Multicomponent intervention (MCI)","Healthy Aging Lifestyle Education (HALE)"],"relevance_confidence":100,"source_quality_score":100,"freshness_score":50,"publication_state":"published","match_explanation":"Title contains controlled term: sarcopenia.","quality_checked_at":"2026-09-25T04:15:37.666886+00:00","duplicate_cluster_key":"id:nct02582138","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2016-01-01 to 2018-12-01","comparator":"Healthy Aging Lifestyle Education (HALE)","confidence":"structured-source","population":"ALL · 70 Years","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T04:15:35.436Z","intervention":["Multicomponent intervention (MCI)","Healthy Aging Lifestyle Education (HALE)"],"participants":1500,"study_design":"RANDOMIZED · PARALLEL · PREVENTION · SINGLE","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["Incident of major mobility disability — 36 months","Changes in lower extremity physical performance — 36 months","Changes in upper extremity muscle strength — 36 months","Changes in functional status (activities of daily living) — 36 months","Changes in functional status (instrumental activities of daily living) — 36 months","Changes in crude appendicular lean mass — 36 months","Changes in body mass index-adjusted appendicular lean mass — 36 months","Persistent mobility disability — 36 months","Changes in body weight — 36 months","Changes in body mass index — 36 months","Changes in mid-arm circumference — 36 months","Changes in waist circumference — 36 months","Changes in hip circumference — 36 months","Changes in calf circumference — 36 months","Changes in nutritional status — 36 months","Changes in cognitive function — 36 months","Changes in mood — 36 months","Incidence of self-reported falls — 36 months","Incidence of injurious falls — 36 months","Changes in quality of life — 36 months"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"sarcopenia","is_published":true,"match_reasons":["Title contains controlled term: sarcopenia.","Abstract contains controlled term: sarcopenia.","Source terminology contains: sarcopenia.","Title supplies longevity context: frailty, frail.","Study type is explicitly identified as INTERVENTIONAL."],"matched_fields":["title","abstract","controlled terminology","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Sarcopenia","slug":"sarcopenia"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/90706","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}