{"type":"trials","record":{"id":90726,"source_id":"clinicaltrials-gov","external_id":"NCT01477086","title":"Prevalence and Pathophysiology of Sarcopenia in the Elderly Patient With Hip Fracture","brief_summary":"Sarcopenia is the loss of muscle mass and function that accompanies aging. The term sarcopenia comes from the Greek \"sarx\" (flesh) and \"penia\" (loss). Sarcopenia is a topic of great interest to geriatricians, and from 2010 discussing the possibility of considering it as a geriatric syndrome. Diagnostic criteria are reduced muscle mass, reduced strength and impaired physical performance. The presence of muscle mass reduction set presarcopenia diagnosis, when combined with one of the other two are talking about sarcopenia and when are the three is defined as severe sarcopenia. The hypothesis of our study is that sarcopenia is highly prevalent in older people with hip fracture. The increase in inflammatory indices of older people, along with bed rest, represent factors that accelerate the development of sarcopenia. These factors together could be the base of the high percentage of patients who do not recover the degree of autonomy before the fracture.","overall_status":"Completed","phases":[],"study_type":"OBSERVATIONAL","sponsor":"Hospital Viamed Valvanera, Spain","enrollment":198,"countries":["Spain"],"start_date":"2012-01-01","completion_date":"2015-12-01","last_update_date":"2016-02-05","source_url":"https://clinicaltrials.gov/study/NCT01477086","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Completed. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T04:15:35.799123+00:00","last_seen_at":"2026-09-25T04:15:35.417+00:00","metadata":{"sex":"ALL","acronym":"PREFISSARC","age_range":"65 Years","comparator":null,"organization":"Hospital Viamed Valvanera, Spain","interventions":[],"registry_source":"ClinicalTrials.gov","outcome_measures":["Sarcopenia prevalence — Within the first 72 hours of admission.","Relationship inflammatory indices and sarcopenia. — A admission and at discharge, after 30 days.","Prevalence of falls. — During the six months prior to admission.","Acute mortality. — During admission","Relationship sarcopenia and frailty. — At admission and after 30 days.","Relationship sarcopenia and Barthel index. — At admission and after 30 days ."],"design_description":null,"source_has_results":false},"controlled_terms":["Sarcopenia","Hip Fracture","Frailty"],"relevance_confidence":100,"source_quality_score":100,"freshness_score":35,"publication_state":"published","match_explanation":"Title contains controlled term: sarcopenia.","quality_checked_at":"2026-09-25T04:15:37.666886+00:00","duplicate_cluster_key":"id:nct01477086","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2012-01-01 to 2015-12-01","comparator":null,"confidence":"structured-source","population":"ALL · 65 Years","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T04:15:35.440Z","intervention":[],"participants":198,"study_design":"OBSERVATIONAL","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["Sarcopenia prevalence — Within the first 72 hours of admission.","Relationship inflammatory indices and sarcopenia. — A admission and at discharge, after 30 days.","Prevalence of falls. — During the six months prior to admission.","Acute mortality. — During admission","Relationship sarcopenia and frailty. — At admission and after 30 days.","Relationship sarcopenia and Barthel index. — At admission and after 30 days ."],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"sarcopenia","is_published":true,"match_reasons":["Title contains controlled term: sarcopenia.","Abstract contains controlled term: sarcopenia.","Source terminology contains: sarcopenia.","Title supplies longevity context: elderly.","Study type is explicitly identified as OBSERVATIONAL."],"matched_fields":["title","abstract","controlled terminology","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Sarcopenia","slug":"sarcopenia"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/90726","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}