{"type":"trials","record":{"id":93414,"source_id":"clinicaltrials-gov","external_id":"NCT03033953","title":"Effects of Native Whey or Milk Supplementation on Adaptations to 12 Weeks of Strength Training in Young and Elderly","brief_summary":"The aim of this study is to investigate the long term adaptations to 11 (elderly) or 12 (young) weeks of strength training when supplemented with native whey or milk. The investigators hypothesize that native whey will give greater increases in muscle hypertrophy and strength than milk.","overall_status":"Completed","phases":[],"study_type":"INTERVENTIONAL","sponsor":"Norwegian School of Sport Sciences","enrollment":66,"countries":["Norway"],"start_date":"2014-08-01","completion_date":"2016-11-01","last_update_date":"2017-01-27","source_url":"https://clinicaltrials.gov/study/NCT03033953","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Completed. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T05:35:08.159429+00:00","last_seen_at":"2026-09-25T05:35:07.553+00:00","metadata":{"sex":"ALL","acronym":null,"age_range":"20 Years","comparator":"Milk supplementation","organization":"Norwegian School of Sport Sciences","interventions":["Native whey","Milk","Strength training"],"registry_source":"ClinicalTrials.gov","outcome_measures":["Lean mass — Before the training intervention","Lean mass — After 11-12 weeks of strength training","Thigh muscle cross sectional area — Before the training intervention","Thigh muscle cross sectional area — After 11-12 weeks of strength training","Pectoralis muscle cross sectional area — Before the training intervention","Pectoralis muscle cross sectional area — After 11-12 weeks of strength training","Arm cross sectional area — Before the training intervention","Arm cross sectional area — After 11-12 weeks of strength training","Thickness of the lateral vasti — Before the training intervention","Thickness of the lateral vasti — After 11-12 weeks of strength training","1 repetition maximum in leg press — Before the training intervention","1 repetition maximum in leg press — After 11-12 weeks of strength training","1 repetition maximum in bench press — Before the training intervention","1 repetition maximum in bench press — After 11-12 weeks of strength training","Ratio of phosphorylated to total ribosomal protein S6 kinase beta-1(P70S6K) change from baseline — 30 min before and 2…","Phosphorylation of phosphorylated to total eukaryotic elongation factor 2 (eEF-2) change from baseline — 30 min before…","Phosphorylation of phosphorylated to total eukaryotic translation initiation factor 4E-binding protein 1 (4EBP-1) chang…","Plasma amino acid concentration — 60 min before and 45, 60, 75 and 120 min after exercise and protein supplement intake…","Muscle force generating capacity change from baseline — 15 min before, 10 min, 2.5 hours and 24 hours after exercise an…","Serum glucose — 60 min before and 45, 60, 75 and 120 min after exercise and protein supplement intake, before the train…"],"design_description":"RANDOMIZED · PARALLEL · BASIC SCIENCE · QUADRUPLE","source_has_results":false},"controlled_terms":["Healthy","Young","Elderly","Native whey","Milk","Strength training"],"relevance_confidence":100,"source_quality_score":100,"freshness_score":50,"publication_state":"published","match_explanation":"Title contains controlled term: strength training.","quality_checked_at":"2026-09-25T05:35:12.977559+00:00","duplicate_cluster_key":"id:nct03033953","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2014-08-01 to 2016-11-01","comparator":"Milk supplementation","confidence":"structured-source","population":"ALL · 20 Years","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T05:35:07.575Z","intervention":["Native whey","Milk","Strength training"],"participants":66,"study_design":"RANDOMIZED · PARALLEL · BASIC SCIENCE · QUADRUPLE","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["Lean mass — Before the training intervention","Lean mass — After 11-12 weeks of strength training","Thigh muscle cross sectional area — Before the training intervention","Thigh muscle cross sectional area — After 11-12 weeks of strength training","Pectoralis muscle cross sectional area — Before the training intervention","Pectoralis muscle cross sectional area — After 11-12 weeks of strength training","Arm cross sectional area — Before the training intervention","Arm cross sectional area — After 11-12 weeks of strength training","Thickness of the lateral vasti — Before the training intervention","Thickness of the lateral vasti — After 11-12 weeks of strength training","1 repetition maximum in leg press — Before the training intervention","1 repetition maximum in leg press — After 11-12 weeks of strength training","1 repetition maximum in bench press — Before the training intervention","1 repetition maximum in bench press — After 11-12 weeks of strength training","Ratio of phosphorylated to total ribosomal protein S6 kinase beta-1(P70S6K) change from baseline — 30 min before and 2…","Phosphorylation of phosphorylated to total eukaryotic elongation factor 2 (eEF-2) change from baseline — 30 min before…","Phosphorylation of phosphorylated to total eukaryotic translation initiation factor 4E-binding protein 1 (4EBP-1) chang…","Plasma amino acid concentration — 60 min before and 45, 60, 75 and 120 min after exercise and protein supplement intake…","Muscle force generating capacity change from baseline — 15 min before, 10 min, 2.5 hours and 24 hours after exercise an…","Serum glucose — 60 min before and 45, 60, 75 and 120 min after exercise and protein supplement intake, before the train…"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"resistance-training","is_published":true,"match_reasons":["Title contains controlled term: strength training.","Abstract contains controlled term: strength training.","Source terminology contains: strength training.","Title supplies longevity context: elderly.","Study type is explicitly identified as INTERVENTIONAL."],"matched_fields":["title","abstract","controlled terminology","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Resistance training","slug":"resistance-training"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/93414","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}