{"type":"trials","record":{"id":94,"source_id":"clinicaltrials-gov","external_id":"NCT03734419","title":"The Use of Aging Biomarkers in Saliva, Based on DNA Methylation Status in Elovl2 to Predict Biological Age","brief_summary":"There is a big change in our understanding of aging in recent years. Recent researches has revealed clock-like patterns of epigenetic change across in humans. The aging involves a timed epigenetic reprogramming. However, this biological clock which ticks in our DNA is affected by our experience, diet, stress, etc. and it could be changed by experience and life style potentially. The purpose of this study is to develop and test non-invasive biomarkers based on methylation changes in ELOVL2-AS1 gene in saliva samples using a next generation sequencing.","overall_status":"Withdrawn","phases":[],"study_type":"OBSERVATIONAL","sponsor":"HKGepitherapeutics","enrollment":0,"countries":[],"start_date":"2019-12-01","completion_date":"2021-12-01","last_update_date":"2023-12-21","source_url":"https://clinicaltrials.gov/study/NCT03734419","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Withdrawn. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-14T02:44:59.586437+00:00","last_seen_at":"2026-09-15T00:18:32.38+00:00","metadata":{"acronym":null,"organization":"HKGepitherapeutics","source_has_results":false},"controlled_terms":[],"relevance_confidence":68,"source_quality_score":100,"freshness_score":65,"publication_state":"published","match_explanation":"Published automatically with 68% topic confidence after controlled-term evaluation.","quality_checked_at":"2026-09-15T02:15:56.576005+00:00","duplicate_cluster_key":"registry:nct03734419","duplicate_of_id":null,"clinical_trial_topics":[{"topic_slug":"partial-reprogramming","is_published":true,"match_reasons":["Legacy trial evaluated automatically against controlled title, summary, and longevity-context rules."],"matched_fields":["abstract"],"relevance_score":68,"intelligence_topics":{"name":"Partial reprogramming","slug":"partial-reprogramming"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/94","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}