{ "release_id": "longevity-evidence-landscape-2026-10-v1", "version": "1.0.0", "title": "Immortal.life Longevity Evidence Landscape — October 2026", "description": "A dated, source-linked comparison of research, human evidence, registered trials, visible trial results, funding activity, institutions, and evidence gaps across all 180 immortal.life longevity topics.", "released_on": "2026-10-04", "record_count": 180, "source_snapshot_generated_at": "2026-10-04T02:34:09.818049+00:00", "method_version": "evidence-gap-atlas-2026-10-v1", "citation": "Immortal.life. (2026). Immortal.life Longevity Evidence Landscape — October 2026 (Version 1.0.0) [Data set]. Zenodo. https://doi.org/10.5281/zenodo.23131145", "rights_notice": "The original selection, arrangement, field definitions, and documentation are made available with attribution under CC BY 4.0. Underlying source facts and identifiers remain subject to the terms of their originating sources. This release contains aggregate topic-level observations, not republished source records.", "scope": "Aggregate topic-level observations across the complete 180-topic immortal.life taxonomy.", "limitations": [ "Counts describe records visible in the frozen immortal.life index snapshot, not all evidence everywhere.", "Counts do not establish benefit, safety, causality, consensus, scientific quality, institutional quality, funding impact, or unmet medical need.", "Trial registration is not a result, and registered enrollment may be planned or actual.", "A missing matched layer is a coverage observation, not proof that the evidence does not exist." ], "fields": [ { "name": "topic_slug", "type": "string", "meaning": "Stable immortal.life topic identifier." }, { "name": "topic_name", "type": "string", "meaning": "Reader-facing topic name." }, { "name": "topic_description", "type": "string", "meaning": "Short scope definition maintained by immortal.life." }, { "name": "domain_slug", "type": "string", "meaning": "Stable identifier for one of the nine longevity domains." }, { "name": "domain_name", "type": "string", "meaning": "Reader-facing longevity domain." }, { "name": "snapshot_refreshed_at", "type": "ISO 8601 datetime", "meaning": "Time of the verified topic snapshot frozen into this release." }, { "name": "research_records", "type": "integer", "meaning": "Published, quality-eligible research records matched to the topic." }, { "name": "human_study_records", "type": "integer", "meaning": "Matched research records classified as human evidence. This is a study-type count, not proof of benefit." }, { "name": "preclinical_records", "type": "integer", "meaning": "Matched records classified as laboratory, animal, or other preclinical evidence." }, { "name": "randomized_human_records", "type": "integer", "meaning": "Matched research records classified as randomized human studies." }, { "name": "evidence_syntheses", "type": "integer", "meaning": "Matched systematic reviews, meta-analyses, guidelines, or other classified syntheses." }, { "name": "registered_trials", "type": "integer", "meaning": "Matched clinical-trial registrations. Registration is not a result." }, { "name": "active_or_recruiting_trials", "type": "integer", "meaning": "Matched registrations carrying an active or recruiting status in their source registry." }, { "name": "trials_with_visible_results", "type": "integer", "meaning": "Matched registrations exposing structured results in a connected registry." }, { "name": "registered_enrollment", "type": "integer", "meaning": "Sum of planned or actual enrollment reported by matched registrations; registry records may not distinguish the two." }, { "name": "recent_research_records", "type": "integer", "meaning": "Matched research records inside the Atlas recent-activity window." }, { "name": "trend_direction", "type": "string", "meaning": "Deterministic recent publication-activity direction used by the dossier." }, { "name": "university_activity_links", "type": "integer", "meaning": "Source-matched university-topic work links, not a count of university quality or teaching performance." }, { "name": "direct_grant_records", "type": "integer", "meaning": "Matched direct grant records from permitted official grant sources." }, { "name": "publication_linked_funding_records", "type": "integer", "meaning": "Funding award entities acknowledged by matched publications; this does not measure spending or impact." }, { "name": "regulatory_records", "type": "integer", "meaning": "Matched official regulatory notices; relevance is jurisdiction-, product-, indication-, and date-specific." }, { "name": "integrity_events", "type": "integer", "meaning": "Matched corrections, retractions, withdrawals, or other indexed research-integrity events." }, { "name": "latest_source_change", "type": "date or null", "meaning": "Most recent meaningful source-linked change visible in the topic snapshot." }, { "name": "leading_university", "type": "string or null", "meaning": "Institution with the most matched five-year activity in the indexed topic; not a quality ranking." }, { "name": "leading_university_country", "type": "string or null", "meaning": "Country reported for the leading indexed institution." }, { "name": "leading_funder", "type": "string or null", "meaning": "Most visible matched funder name in direct-grant or publication-acknowledgement data." }, { "name": "leading_country", "type": "string or null", "meaning": "Country with the most matched five-year university-topic work links." }, { "name": "leading_country_code", "type": "string or null", "meaning": "Country code supplied with the indexed institution data." }, { "name": "gap_research_without_classified_human", "type": "boolean", "meaning": "Research records are present but no matched record is currently classified as human evidence." }, { "name": "gap_trials_without_visible_results", "type": "boolean", "meaning": "Trial registrations are present but no structured results are visible in connected registries." }, { "name": "gap_funding_without_matched_trial", "type": "boolean", "meaning": "Funding 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"gap_human_without_synthesis": true }, { "topic_slug": "lipid-metabolism-aging", "topic_name": "Lipid metabolism and ageing", "topic_description": "Age-related lipid handling, lipid droplets and membrane composition.", "domain_slug": "ageing-mechanisms", "domain_name": "Ageing mechanisms", "snapshot_refreshed_at": "2026-10-04T01:23:00.246424+00:00", "research_records": 308, "human_study_records": 9, "preclinical_records": 45, "randomized_human_records": 5, "evidence_syntheses": 1, "registered_trials": 1, "active_or_recruiting_trials": 0, "trials_with_visible_results": 1, "registered_enrollment": 22, "recent_research_records": 95, "trend_direction": "growing", "university_activity_links": 6183, "direct_grant_records": 34, "publication_linked_funding_records": 0, "regulatory_records": 0, "integrity_events": 0, "latest_source_change": "2026-10-03T13:03:55.405366+00:00", "leading_university": null, "leading_university_country": null, "leading_funder": "National Institute on Aging", 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