Research record

Protocol for the RETHINK study: a randomised, double-blind, parallel-group, non-inferiority clinical trial comparing acetaminophen and NSAIDs for treatment of chronic pain in elderly patients with osteoarthritis of the hip and knee.

Human study published by BMJ open, indexed because it matched monitored longevity research terms. Inclusion in this index does not establish that an intervention is effective or safe.

Plain-language guide

Five questions to ask about this record

What this is
human-study record from BMJ open.
Why it may matter
It matched a longevity topic and may show how that evidence area is developing.
Evidence
Automated topic match 100%; this is not a medical rating.
Main limitation
One research record does not prove safety, effectiveness, or usefulness for an individual.
What changed
Source metadata was published or refreshed February 10, 2023.
Where to verify
Open the primary source below for methods, population, results, and limitations.
Published
February 10, 2023
Journal
BMJ open
Authors
Makoto Endo, Shinya Kawahara, Taishi Sato, Masami Tokunaga, Toshihiko Hara, Taro Mawatari, Tsutomu Kawano, Sadamoto Zenda, Tempei Miyaji, Mototsugu Shimokawa, Sanae Sakamoto, Toshio Takano, Masumi Miyake, Hiroyuki Aono, Yasuharu Nakashima, RETHINK study group
DOI
10.1136/bmjopen-2022-068220
Evidence class
human-study
Record status
published
Match confidence
100%
Source feed
PubMed
Automated source synopsis

Human study published by BMJ open, indexed because it matched monitored longevity research terms. Inclusion in this index does not establish that an intervention is effective or safe.

Evidence snapshot

What the source actually supports

Evidence stage
Human study
Study design
Clinical Trial Protocol; Journal Article; Research Support, Non-U.S. Gov't
Evidence population
Human evidence
Participants
Not reported
Population
Not reported
Duration
Not reported
Intervention
Comparator
Not reported
Outcomes measured
Reported result
No reusable finding-level result is available in this record.

Main limitationBibliographic metadata identifies the record but does not provide enough reusable detail to summarize its population, comparison, findings, or effect size.

Safety and approvalThis index record does not establish safety, effectiveness, dose, or suitability for any person. A publication record is not a regulatory approval or treatment recommendation.

Source supportBibliographic citation metadata and controlled indexing terms only. Read the linked source for methods and results.

Evidence stage · human-studyThis describes the study type, not whether an intervention is safe or effective.
Lab or animalHuman studyRandomized trialEvidence synthesis
Why this record appears here · 100% topic match

The title, summary, or source keywords matched one or more topics followed by immortal.life. A higher percentage means a stronger topic match; it does not rate safety, effectiveness, or study quality.

  • Chronic pain and ageing · 100%Title contains controlled topic terminology. Source terminology contains a controlled topic term. Title supplies ageing or longevity context.
  • Joint and cartilage ageing · 100%Title contains controlled topic terminology. Source terminology contains a controlled topic term. Title supplies ageing or longevity context.

Automated source check 95% · update recency 50%. These figures help sort records; they are not medical ratings.

BibTeX · RIS

chronic pain agingjoint cartilage aging
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