Research record

Personalized functional topography-based multisite brain age prediction modeling reveals divergent neurodevelopment in major depression.

Research record published by Proceedings of the National Academy of Sciences of the United States of America, indexed because it matched monitored longevity research terms. Inclusion in this index does not establish that an intervention is effective or safe.

Plain-language guide

Five questions to ask about this record

What this is
research-record record from Proceedings of the National Academy of Sciences of the United States of America.
Why it may matter
It matched a longevity topic and may show how that evidence area is developing.
Evidence
Automated topic match 100%; this is not a medical rating.
Main limitation
One research record does not prove safety, effectiveness, or usefulness for an individual.
What changed
Source metadata was published or refreshed March 11, 2026.
Where to verify
Open the primary source below for methods, population, results, and limitations.
Published
March 11, 2026
Journal
Proceedings of the National Academy of Sciences of the United States of America
Authors
Chenxuan Pang, Xiaoyi Sun, Jianlong Zhao, Xinyuan Liang, Lianglong Sun, Qixiang Lin, Jinrong Sun, Xiaowen Lu, Qiangli Dong, Liang Zhang, Xiaoqin Wang, Dongtao Wei, Yuan Chen, Bangshan Liu, Chu-Chung Huang, Yanting Zheng, Yankun Wu, Taolin Chen, Yuqi Cheng, Xiufeng Xu, Qiyong Gong, Tianmei Si, Shijun Qiu, Ching-Po Lin, Jingliang Cheng, Yanqing Tang, Fei Wang, Jiang Qiu, Peng Xie, Lingjiang Li
DOI
10.1073/pnas.2519586123
Evidence class
research-record
Record status
published
Match confidence
100%
Source feed
PubMed
Automated source synopsis

Research record published by Proceedings of the National Academy of Sciences of the United States of America, indexed because it matched monitored longevity research terms. Inclusion in this index does not establish that an intervention is effective or safe.

Evidence snapshot

What the source actually supports

Evidence stage
Research record
Study design
Journal Article; Multicenter Study
Evidence population
Not reported in reusable metadata
Participants
Not reported
Population
Not reported
Duration
Not reported
Intervention
Comparator
Not reported
Outcomes measured
Reported result
No reusable finding-level result is available in this record.

Main limitationBibliographic metadata identifies the record but does not provide enough reusable detail to summarize its population, comparison, findings, or effect size.

Safety and approvalThis index record does not establish safety, effectiveness, dose, or suitability for any person. A publication record is not a regulatory approval or treatment recommendation.

Source supportBibliographic citation metadata and controlled indexing terms only. Read the linked source for methods and results.

Evidence stage · research-recordThis describes the study type, not whether an intervention is safe or effective.
Lab or animalHuman studyRandomized trialEvidence synthesis
Why this record appears here · 100% topic match

The title, summary, or source keywords matched one or more topics followed by immortal.life. A higher percentage means a stronger topic match; it does not rate safety, effectiveness, or study quality.

  • Brain-age imaging · 100%Title contains controlled topic terminology. Source terminology contains a controlled topic term. Source terminology supplies ageing or longevity context.

Automated source check 95% · update recency 85%. These figures help sort records; they are not medical ratings.

BibTeX · RIS

brain age imaging
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