Research record

Roles of the Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR pathways in controlling growth and sensitivity to therapy-implications for cancer and aging

Research record published by Aging, indexed because it matched monitored longevity research terms. Inclusion in this index does not establish that an intervention is effective or safe.

Plain-language guide

Five questions to ask about this record

What this is
research-record record from Aging.
Why it may matter
It matched a longevity topic and may show how that evidence area is developing.
Evidence
Automated topic match 100%; this is not a medical rating.
Main limitation
One research record does not prove safety, effectiveness, or usefulness for an individual.
What changed
Source metadata was published or refreshed March 10, 2011.
Where to verify
Open the primary source below for methods, population, results, and limitations.
Published
March 10, 2011
Journal
Aging
Authors
Linda S. Steelman, William H. Chappell, Stephen Lee Abrams, Christian Kempf, Jacquelyn M. Long, Piotr M. Laidler, Sanja Mijatović, Danijela Maksimović‐Ivanić, Franca Stivala, María Clorinda Mazzarino, Marco Donia, Paolo Fagone, Graziella Malaponte, Ferdinando Nicoletti, Massimo Libra, Michèle Milella, Agostino Tafuri, Antonio Bonati, Jörg Bäsecke, Lucio Cocco, Camilla Evangelisti, Alberto Maria Martelli, Giuseppe Montalto, Melchiorre Cervello, James Andrew McCubrey
DOI
10.18632/aging.100296
Evidence class
research-record
Record status
published
Match confidence
100%
Citations
710
Source feed
OpenAlex
Automated source synopsis

Research record published by Aging, indexed because it matched monitored longevity research terms. Inclusion in this index does not establish that an intervention is effective or safe.

Evidence snapshot

What the source actually supports

Evidence stage
Research record
Study design
article
Evidence population
Not reported in reusable metadata
Participants
Not reported
Population
Not reported
Duration
Not reported
Intervention
Comparator
Not reported
Outcomes measured
Reported result
No reusable finding-level result is available in this record.

Main limitationBibliographic metadata identifies the record but does not provide enough reusable detail to summarize its population, comparison, findings, or effect size.

Safety and approvalThis index record does not establish safety, effectiveness, dose, or suitability for any person. A publication record is not a regulatory approval or treatment recommendation.

Source supportBibliographic citation metadata and controlled indexing terms only. Read the linked source for methods and results.

Evidence stage · research-recordThis describes the study type, not whether an intervention is safe or effective.
Lab or animalHuman studyRandomized trialEvidence synthesis
Why this record appears here · 100% topic match

The title, summary, or source keywords matched one or more topics followed by immortal.life. A higher percentage means a stronger topic match; it does not rate safety, effectiveness, or study quality.

  • Cancer and ageing · 100%Title contains controlled topic terminology. Source terminology contains a controlled topic term. Title supplies ageing or longevity context.

Automated source check 70% · update recency 35%. These figures help sort records; they are not medical ratings.

BibTeX · RIS

cancer and aging
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