Research record

The Cyclin C-CDK8/19 Mediator kinase module controls PRCC-TFE3 driven senescence in renal epithelium and tumorigenesis in TFE3-RCC.

Research record published by Neoplasia (New York, N.Y.), indexed because it matched monitored longevity research terms. Inclusion in this index does not establish that an intervention is effective or safe.

Plain-language guide

Five questions to ask about this record

What this is
research-record record from Neoplasia (New York, N.Y.).
Why it may matter
It matched a longevity topic and may show how that evidence area is developing.
Evidence
Automated topic match 100%; this is not a medical rating.
Main limitation
One research record does not prove safety, effectiveness, or usefulness for an individual.
What changed
Source metadata was published or refreshed March 16, 2026.
Where to verify
Open the primary source below for methods, population, results, and limitations.
Published
March 16, 2026
Journal
Neoplasia (New York, N.Y.)
Authors
Shoichiro Kuroda, Shintaro Funasaki, Hidekazu Nishizawa, Laura S Schmidt, Ryoma Kurahashi, Takaaki Ito, Yuichiro Arima, Miwa Tanaka, Atsuya Kitada, Amy M James, Hisashi Hasumi, Ryosuke Jikuya, Kazuhide Makiyama, Daisuke Kurotaki, Takashi Minami, Simone Difilippantonio, W Marston Linehan, Yuichi Oike, Tomohiro Sawa, Yasuhito Tanaka, Toshio Suda, Ryuji Yokokawa, Takuro Nakamura, Masaya Baba, Tomomi Kamba
DOI
10.1016/j.neo.2026.101296
Evidence class
research-record
Record status
published
Match confidence
100%
Source feed
PubMed
Automated source synopsis

Research record published by Neoplasia (New York, N.Y.), indexed because it matched monitored longevity research terms. Inclusion in this index does not establish that an intervention is effective or safe.

Evidence snapshot

What the source actually supports

Evidence stage
Research record
Study design
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
Evidence population
Not reported in reusable metadata
Participants
Not reported
Population
Not reported
Duration
Not reported
Intervention
Comparator
Not reported
Outcomes measured
Reported result
No reusable finding-level result is available in this record.

Main limitationBibliographic metadata identifies the record but does not provide enough reusable detail to summarize its population, comparison, findings, or effect size.

Safety and approvalThis index record does not establish safety, effectiveness, dose, or suitability for any person. A publication record is not a regulatory approval or treatment recommendation.

Source supportBibliographic citation metadata and controlled indexing terms only. Read the linked source for methods and results.

Evidence stage · research-recordThis describes the study type, not whether an intervention is safe or effective.
Lab or animalHuman studyRandomized trialEvidence synthesis
Why this record appears here · 100% topic match

The title, summary, or source keywords matched one or more topics followed by immortal.life. A higher percentage means a stronger topic match; it does not rate safety, effectiveness, or study quality.

  • Cancer and ageing · 100%Title contains controlled topic terminology. Source terminology contains a controlled topic term. Title supplies ageing or longevity context.
  • Senolytics · 65%Source terminology contains a controlled topic term. Title supplies ageing or longevity context.

Automated source check 95% · update recency 85%. These figures help sort records; they are not medical ratings.

BibTeX · RIS

cancer and agingsenolytics
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