Research record

Chronic rapamycin restores brain vascular integrity and function through NO synthase activation and improves memory in symptomatic mice modeling Alzheimer's disease.

Preclinical research published by Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow an…, indexed because it matched monitored longevity research terms. Inclusion in this index does not establis

Plain-language guide

Five questions to ask about this record

What this is
preclinical record from Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.
Why it may matter
It matched a longevity topic and may show how that evidence area is developing.
Evidence
Automated topic match 100%; this is not a medical rating.
Main limitation
One research record does not prove safety, effectiveness, or usefulness for an individual.
What changed
Source metadata was published or refreshed June 26, 2013.
Where to verify
Open the primary source below for methods, population, results, and limitations.
Published
June 26, 2013
Journal
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism
Authors
Ai-Ling Lin, Wei Zheng, Jonathan J Halloran, Raquel R Burbank, Stacy A Hussong, Matthew J Hart, Martin Javors, Yen-Yu Ian Shih, Eric Muir, Rene Solano Fonseca, Randy Strong, Arlan G Richardson, James D Lechleiter, Peter T Fox, Veronica Galvan
DOI
10.1038/jcbfm.2013.82
Evidence class
preclinical
Record status
published
Match confidence
100%
Source feed
PubMed
Automated source synopsis

Preclinical research published by Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow an…, indexed because it matched monitored longevity research terms. Inclusion in this index does not establish that an intervention is effective or safe.

Evidence snapshot

What the source actually supports

Evidence stage
Preclinical research
Study design
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
Evidence population
Preclinical (laboratory or animal research)
Participants
Not reported
Population
Not reported
Duration
Not reported
Intervention
Comparator
Not reported
Outcomes measured
Reported result
No reusable finding-level result is available in this record.

Main limitationPreclinical findings may not apply to people; the reusable source metadata does not provide enough detail to assess the result.

Safety and approvalThis index record does not establish safety, effectiveness, dose, or suitability for any person. A publication record is not a regulatory approval or treatment recommendation.

Source supportBibliographic citation metadata and controlled indexing terms only. Read the linked source for methods and results.

Evidence stage · preclinicalThis describes the study type, not whether an intervention is safe or effective.
Lab or animalHuman studyRandomized trialEvidence synthesis
Why this record appears here · 100% topic match

The title, summary, or source keywords matched one or more topics followed by immortal.life. A higher percentage means a stronger topic match; it does not rate safety, effectiveness, or study quality.

  • Rapamycin · 100%Title contains controlled topic terminology. Source terminology contains a controlled topic term.

Automated source check 95% · update recency 35%. These figures help sort records; they are not medical ratings.

BibTeX · RIS

rapamycin
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