Clinical trial registry record

Gut-Brain-axis: Targets for Improvement of Cognition in the Elderly

A registered study indexed because it matched monitored longevity research terms. Registry status: Completed. Registration does not establish safety or effectiveness.

Plain-language guide

Five questions to ask about this record

What this is
A clinical study registration, not a result or recommendation.
Why it may matter
The registry currently reports Completed.
Evidence
Registered phase not reported study.
Main limitation
Registration does not prove that the intervention works, is safe, or is available to you.
What changed
Registry metadata was last updated March 31, 2026.
Where to verify
Open the primary registry below for eligibility, locations, contacts, and current status.
Registry ID
NCT04841668
Last registry update
March 31, 2026
Status
Completed
Phase
Phase not reported
Sponsor
Institut d'Investigació Biomèdica de Girona Dr. Josep Trueta
Enrollment
50
Countries
Spain
Match confidence
100%
Source feed
ClinicalTrials.gov
Automated source synopsis

A registered study indexed because it matched monitored longevity research terms. Registry status: Completed. Registration does not establish safety or effectiveness.

Evidence snapshot

What the source actually supports

Evidence stage
Phase not reported
Study design
OBSERVATIONAL
Evidence population
Human clinical study registration
Participants
50
Population
ALL · 65 Years to 80 Years
Duration
2021-04-10 to 2024-12-03
Intervention
Metformin
Comparator
Not reported
Outcomes measured
Gut microbiota composition. — 12 months; Cognitive impairment — 12 months; Audioverbal memory — 12 months; Visual memory — 12 months; Depressive symptomatology — 12 months; Impulsivity — 12 months; Food Addiction — 12 months; Behavioral inhibition — 12 months; Behavioral activation — 12 months; Visoconstructive function — 12 months; Visuospatial perception — 12 months; Naming — 12 months; Selective and alternating attention — 12 months; Attention and working memory — 12 months; Inhibition — 12 months; Phonemic verbal fluency — 12 months; Semantic verbal fluency — 12 months; The percentage of time in glucose target range (glucose level 70mg/dl-180mg/dl) — 12 months; Effect on gut microbiota — 12 months; The percentage of time in glucose range (glucose level below 100 mg/dl) — 12 months
Reported result
No reusable finding-level result is available in this record.

Main limitationThis is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.

Safety and approvalEligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians. Trial registration is not regulatory approval and does not establish that an intervention is available.

Source supportStructured registry protocol metadata; no finding-level conclusion is generated.

Trial stage · Phase not reportedA trial phase describes development stage; it does not establish a positive result.
Phase 1Phase 2Phase 3Phase 4

Registration and recruitment status do not establish safety, efficacy, or regulatory approval.

Why this record appears here · 100% topic match

The title, summary, or source keywords matched one or more topics followed by immortal.life. A higher percentage means a stronger topic match; it does not rate safety, effectiveness, or study quality.

  • Metformin · 100%Summary contains controlled topic terminology. Source terminology contains a controlled topic term. Title supplies ageing or longevity context.

Automated source check 100% · update recency 85%. These figures help sort records; they are not medical ratings.

metformin
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