Clinical trial registry record

Senolytic Agent Improve the Benefit of Platelet-Rich Plasma and Losartan

A registered PHASE1, PHASE2 study indexed because it matched monitored longevity research terms. Registry status: Unknown. Registration does not establish safety or effectiveness.

Plain-language guide

Five questions to ask about this record

What this is
A clinical study registration, not a result or recommendation.
Why it may matter
The registry currently reports Unknown.
Evidence
Registered phase 1, phase 2 study.
Main limitation
Registration does not prove that the intervention works, is safe, or is available to you.
What changed
Registry metadata was last updated April 16, 2024.
Where to verify
Open the primary registry below for eligibility, locations, contacts, and current status.
Registry ID
NCT05025956
Last registry update
April 16, 2024
Status
Unknown
Phase
Phase 1, Phase 2
Sponsor
Steadman Philippon Research Institute
Enrollment
68
Countries
United States
Match confidence
100%
Source feed
ClinicalTrials.gov
Automated source synopsis

A registered PHASE1, PHASE2 study indexed because it matched monitored longevity research terms. Registry status: Unknown. Registration does not establish safety or effectiveness.

Evidence snapshot

What the source actually supports

Evidence stage
Phase 1, Phase 2
Study design
RANDOMIZED · PARALLEL · TREATMENT · QUADRUPLE
Evidence population
Human clinical study registration
Participants
68
Population
ALL · 18 Years to 80 Years
Duration
2021-10-24 to 2024-10-31
Intervention
Fisetin; Placebo
Comparator
Placebo group (control group)
Outcomes measured
Incidence of Treatment-Emergent Adverse Events — From date of study drug dosing until the end of the study, an average…; Patient Reported Outcomes Questionnaire-Modified Harris Hip Score (mHHS) — Baseline, 8-12 weeks post-op, 6 months post-…; Patient Reported Outcomes Questionnaire- Hip Outcome Score: activities of daily living and sports subscales (HOS-ADL, H…; Patient Reported Outcomes Questionnaire-Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) — Baseli…; Patient Reported Outcomes Questionnaire-Optum Short Form physical and mental component scores (SF-12 PCS and SF-12 MCS)…; Patient Reported Outcomes Questionnaire-Tegner Activity Scale — Baseline, 8-12 weeks post-op, 6 months post-op, and 12…; Patient Reported Outcomes Questionnaire-Numeric Rating Scale for Hip Pain — Baseline, 8-12 weeks post-op, 6 months post…; Patient Reported Outcomes Questionnaire-Patient satisfaction with surgical outcome — Baseline, 8-12 weeks post-op, 6 mo…; Multi and singleplex immunoassays and flow cytometry senescence and SASP marker assessment of peripheral blood — Baseli…; Incidence of revision arthroscopy or other hip surgery required post initial arthroscopy — From day of initial surgery…
Reported result
No reusable finding-level result is available in this record.

Main limitationThis is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.

Safety and approvalEligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians. Trial registration is not regulatory approval and does not establish that an intervention is available.

Source supportStructured registry protocol metadata; no finding-level conclusion is generated.

Trial stage · Phase 1, Phase 2A trial phase describes development stage; it does not establish a positive result.
Phase 1Phase 2Phase 3Phase 4

Registration and recruitment status do not establish safety, efficacy, or regulatory approval.

Why this record appears here · 100% topic match

The title, summary, or source keywords matched one or more topics followed by immortal.life. A higher percentage means a stronger topic match; it does not rate safety, effectiveness, or study quality.

  • Senolytics · 100%Title contains controlled topic terminology. Summary contains controlled topic terminology. Summary supplies ageing or longevity context.

Automated source check 100% · update recency 65%. These figures help sort records; they are not medical ratings.