Clinical trial registry record

Methylphenidate and Cognitive Training in Elderly

A registered PHASE2 study indexed because it matched monitored longevity research terms. Registry status: Completed. Registration does not establish safety or effectiveness.

Plain-language guide

Five questions to ask about this record

What this is
A clinical study registration, not a result or recommendation.
Why it may matter
The registry currently reports Completed.
Evidence
Registered phase 2 study.
Main limitation
Registration does not prove that the intervention works, is safe, or is available to you.
What changed
Registry metadata was last updated December 11, 2025.
Where to verify
Open the primary registry below for eligibility, locations, contacts, and current status.
Registry ID
NCT03280251
Last registry update
December 11, 2025
Status
Completed
Phase
Phase 2
Sponsor
University Hospital, Lille
Enrollment
31
Countries
France
Match confidence
100%
Source feed
ClinicalTrials.gov
Automated source synopsis

A registered PHASE2 study indexed because it matched monitored longevity research terms. Registry status: Completed. Registration does not establish safety or effectiveness.

Evidence snapshot

What the source actually supports

Evidence stage
Phase 2
Study design
RANDOMIZED · PARALLEL · TREATMENT · TRIPLE
Evidence population
Human clinical study registration
Participants
31
Population
ALL · 55 Years to 75 Years
Duration
2018-09-19 to 2020-03-11
Intervention
Methylphenidate; Placebo; CogniPlus software; Pseudo cognitive training
Comparator
Not reported
Outcomes measured
The difference of the average response time to a choice task at inclusion and at the end of treatment (after 6 weeks) —…; Change from baseline the composite cognitive functions — Baseline, at 6 weeks, at 12 weeks; Change from baseline of the results to task on a driving simulator — Baseline, at 6 weeks, at 12 weeks; Behavior Rating Inventory of Executive Function (BRIEF-A) — Baseline, at 6 weeks, at 12 weeks; Hospital Anxiety and Depression scale (HAD) — Baseline, at 6 weeks, at 12 weeks; Number of undesirable effects of treatment — at 2 weeks, at 4 weeks, at 6 weeks, at 12 weeks; Change from baseline the parameters of structured cognitive training (CogniPlus®) — Baseline, at 6 weeks, at 12 weeks; Resting state EEG — Baseline, at 6 weeks, at 12 weeks; resting state functional MRI — Baseline, at 6 weeks, at 12 weeks
Reported result
No reusable finding-level result is available in this record.

Main limitationThis is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.

Safety and approvalEligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians. Trial registration is not regulatory approval and does not establish that an intervention is available.

Source supportStructured registry protocol metadata; no finding-level conclusion is generated.

Trial stage · Phase 2A trial phase describes development stage; it does not establish a positive result.
Phase 1Phase 2Phase 3Phase 4

Registration and recruitment status do not establish safety, efficacy, or regulatory approval.

Why this record appears here · 100% topic match

The title, summary, or source keywords matched one or more topics followed by immortal.life. A higher percentage means a stronger topic match; it does not rate safety, effectiveness, or study quality.

  • Cognitive training · 100%Title contains controlled topic terminology. Summary contains controlled topic terminology. Source terminology contains a controlled topic term. Title supplies ageing or longevity context.

Automated source check 100% · update recency 85%. These figures help sort records; they are not medical ratings.