Clinical trial registry record

Reducing High-Risk Geriatric Polypharmacy Via EHR Nudges R01 Trial

A registered study indexed because it matched monitored longevity research terms. Registry status: Active Not Recruiting. Registration does not establish safety or effectiveness.

Plain-language guide

Five questions to ask about this record

What this is
A clinical study registration, not a result or recommendation.
Why it may matter
The registry currently reports Active Not Recruiting.
Evidence
Registered phase not reported study.
Main limitation
Registration does not prove that the intervention works, is safe, or is available to you.
What changed
Registry metadata was last updated May 26, 2026.
Where to verify
Open the primary registry below for eligibility, locations, contacts, and current status.
Registry ID
NCT05656560
Last registry update
May 26, 2026
Status
Active Not Recruiting
Phase
Phase not reported
Sponsor
Northwestern University
Enrollment
786
Countries
United States
Match confidence
100%
Source feed
ClinicalTrials.gov
Automated source synopsis

A registered study indexed because it matched monitored longevity research terms. Registry status: Active Not Recruiting. Registration does not establish safety or effectiveness.

Evidence snapshot

What the source actually supports

Evidence stage
Phase not reported
Study design
RANDOMIZED · FACTORIAL · HEALTH SERVICES RESEARCH · SINGLE
Evidence population
Human clinical study registration
Participants
786
Population
ALL · 18 Years
Duration
2023-06-08 to 2027-05-31
Intervention
Clinical decision support (CDS)-Commitment nudge; Clinician education; Clinical decision support (CDS)-Justification nudge
Comparator
Not reported
Outcomes measured
The percentage of HRPP with any (1 or more) of the 7 measures of high risk polypharmacy. (Composite measure) — 18 months; The rate of Emergency Department visits per patient -all cause — 18 months; The rate of Emergency Department visits per patient-Adverse drug event (ADE)-specific — 18 months; The rate of hospital admissions per patient-all cause — 18 months; The rate of hospital admissions per patient-ADE-specific — 18 months; The percentage of HRPP patients with a fall condition-drug interaction — 18 months; The percentage of HRPP patients with a fall drug-drug interaction — 18 months; The percentage of HRPP patients with Heart failure-NSAID interaction — 18 months; The percentage of HRPP patients with Heart Failure-thiazolidinedione interaction — 18 months; The percentage of HRPP patients with Heart failure with reduced ejection fraction- non-dihydropyridine calcium channel…; The percentage of HRPP patients with CKD-glyburide/glimepiride interaction — 18 months; The percentage of HRPP patients with CKD-NSAID interaction — 18 months
Reported result
No reusable finding-level result is available in this record.

Main limitationThis is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.

Safety and approvalEligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians. Trial registration is not regulatory approval and does not establish that an intervention is available.

Source supportStructured registry protocol metadata; no finding-level conclusion is generated.

Trial stage · Phase not reportedA trial phase describes development stage; it does not establish a positive result.
Phase 1Phase 2Phase 3Phase 4

Registration and recruitment status do not establish safety, efficacy, or regulatory approval.

Why this record appears here · 100% topic match

The title, summary, or source keywords matched one or more topics followed by immortal.life. A higher percentage means a stronger topic match; it does not rate safety, effectiveness, or study quality.

  • Polypharmacy · 100%Title contains controlled topic terminology. Summary contains controlled topic terminology. Source terminology contains a controlled topic term. Title supplies ageing or longevity context.

Automated source check 100% · update recency 100%. These figures help sort records; they are not medical ratings.

polypharmacy
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