A registered study indexed because it matched monitored longevity research terms. Registry status: Recruiting. Registration does not establish safety or effectiveness.
What the source actually supports
- Evidence stage
- Phase not reported
- Study design
- RANDOMIZED · PARALLEL · PREVENTION · NONE
- Evidence population
- Human clinical study registration
- Participants
- 140
- Population
- ALL · 75 Years
- Duration
- 2026-06-10 to 2029-06-01
- Intervention
- VIVIFRAIL multicomponent exercise program; Mediterranean diet counselling; Extra virgin olive oil supplementation
- Comparator
- VIVIFRAIL
- Outcomes measured
- Change in usual gait speed — Baseline, 6 weeks, 3 months, 6 months, 12 months, 18 months, and 24 months.; Change in physical performance assessed by the Short Physical Performance Battery (SPPB) — Baseline, 6 weeks, 3 months,…; Change in functional independence assessed by the Barthel Index — Baseline, 3 months, 6 months, 12 months, 18 months, a…; Change in health-related quality of life assessed by the EuroQol-5D — Baseline, 6 months, 12 months, 18 months, and 24…; Change in handgrip strength — From baseline to 24 months, according to the study assessment schedule.; Change in sarcopenia status — From baseline to 24 months, according to the study assessment schedule.; Change in muscle thickness assessed by musculoskeletal ultrasound — Baseline, 3 months, 6 months, 12 months, 18 months,…; Change in fear of falling — From baseline to 24 months, according to the study assessment schedule.; Change in adherence to the Mediterranean diet — From baseline to 24 months, according to the study assessment schedule.; Falls and fall-related consequences during follow-up — Throughout the 24-month follow-up period.; Percentage adherence to the VIVIFRAIL exercise program — Throughout the 24-month intervention period.; Change in cognitive performance assessed by the Montreal Cognitive Assessment (MoCA) — Baseline, 3 months, 6 months, 12…; Change in nutritional status assessed by the Mini Nutritional Assessment (MNA) — Baseline, 3 months, 6 months, 12 month…; Change in depressive symptoms assessed by the 15-item Geriatric Depression Scale (GDS-15) — Baseline, 3 months, 6 month…; Number of participants with functional near vision assessed using a simple visual acuity test — Baseline, 3 months, 6 m…; Number of participants with functional distance vision assessed using a simple visual acuity test — Baseline, 3 months,…; Number of participants with functional hearing assessed using the whispered voice test — Baseline, 3 months, 6 months,…; Change in muscle cross-sectional area assessed by musculoskeletal ultrasound — Baseline, 3 months, 6 months, 12 months,…; Change in muscle echo intensity assessed by musculoskeletal ultrasound — Baseline, 3 months, 6 months, 12 months, 18 mo…; Change in muscle ultrasound texture parameters — Baseline, 3 months, 6 months, 12 months, 18 months, and 24 months.
- Reported result
- No reusable finding-level result is available in this record.
Main limitationThis is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.
Safety and approvalEligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians. Trial registration is not regulatory approval and does not establish that an intervention is available.
Source supportStructured registry protocol metadata; no finding-level conclusion is generated.
Registration and recruitment status do not establish safety, efficacy, or regulatory approval.
Why this record appears here · 100% topic match
The title, summary, or source keywords matched one or more topics followed by immortal.life. A higher percentage means a stronger topic match; it does not rate safety, effectiveness, or study quality.
- Exercise · 100%Title contains controlled term: exercise. Abstract contains controlled term: exercise. Source terminology contains: exercise. Title supplies longevity context: older adult. Study type is explicitly identified as INTERVENTIONAL.
Automated source check 100% · update recency 100%. These figures help sort records; they are not medical ratings.