A registered PHASE3 study indexed because it matched monitored longevity research terms. Registry status: Terminated. Registration does not establish safety or effectiveness.
What the source actually supports
- Evidence stage
- Phase 3
- Study design
- RANDOMIZED · PARALLEL · TREATMENT · QUADRUPLE
- Evidence population
- Human clinical study registration
- Participants
- 906
- Population
- ALL · 50 Years
- Duration
- 2014-09-18 to 2018-01-29
- Intervention
- Lampalizumab; Sham
- Comparator
- Not reported
- Outcomes measured
- Change From Baseline in Geographic Atrophy (GA) Area, as Assessed by Fundus Autofluoresence (FAF) at Week 48 — Baseline…; Change From Baseline in GA Area in Complement Factor I (CFI) Positive and Negative Participants at Week 48 — Baseline,…; Change From Baseline in Number of Absolute Scotomatous Points as Assessed by Mesopic Micrometry at Week 48 — Baseline,…; Change From Baseline in Mean Macular Sensitivity as Assessed by Mesopic Microperimetry at Week 48 — Baseline, Week 48; Change From Baseline in Best Corrected Visual Acuity (BCVA) Score as Assessed by Early Treatment Diabetic Retinopathy S…; Percentage of Participants With Less Than 15 Letters Loss From Baseline in BCVA Score at Week 48 — Week 48; Change From Baseline in Low Luminance Visual Acuity (LLVA) as Assessed by ETDRS Chart Under Low Luminance Conditions at…; Percentage of Participants With Less Than 15 Letters Loss From Baseline in LLVA Score at Week 48 — Week 48; Change From Baseline in Binocular Reading Speed as Assessed by Minnesota Low-Vision Reading Test (MNRead) Charts or Rad…; Change From Baseline in Monocular Maximum Reading Speed as Assessed by MNRead Charts or Radner Reading Charts at Week 4…; Change From Baseline in National Eye Institute Visual Functioning Questionnaire 25-item (NEI VFQ-25) Version Composite…; Change From Baseline in NEI VFQ-25 Near Activity Subscale Score at Week 48 — Baseline, Week 48; Change From Baseline in NEI VFQ-25 Distance Activity Subscale Score at Week 48 — Baseline, Week 48; Change From Baseline in Mean Functional Reading Independence (FRI) Index at Week 48 — Baseline, Week 48
- Reported result
- No reusable finding-level result is available in this record.
Main limitationThis is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.
Safety and approvalEligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians. Trial registration is not regulatory approval and does not establish that an intervention is available.
Source supportStructured registry protocol metadata; no finding-level conclusion is generated.
Registration and recruitment status do not establish safety, efficacy, or regulatory approval.
Why this record appears here · 100% topic match
The title, summary, or source keywords matched one or more topics followed by immortal.life. A higher percentage means a stronger topic match; it does not rate safety, effectiveness, or study quality.
- Vision ageing · 100%Title contains controlled topic terminology. Summary contains controlled topic terminology. Title supplies ageing or longevity context.
Automated source check 100% · update recency 50%. These figures help sort records; they are not medical ratings.