Clinical trial registry record

Safety and Efficacy of Switching From Aflibercept to Ranibizumab in Patients With nAMD

A registered PHASE4 study indexed because it matched monitored longevity research terms. Registry status: Completed. Registration does not establish safety or effectiveness.

Plain-language guide

Five questions to ask about this record

What this is
A clinical study registration, not a result or recommendation.
Why it may matter
The registry currently reports Completed.
Evidence
Registered phase 4 study.
Main limitation
Registration does not prove that the intervention works, is safe, or is available to you.
What changed
Registry metadata was last updated February 15, 2019.
Where to verify
Open the primary registry below for eligibility, locations, contacts, and current status.
Registry ID
NCT02161575
Last registry update
February 15, 2019
Status
Completed
Phase
Phase 4
Sponsor
Novartis Pharmaceuticals
Enrollment
103
Countries
Germany, United Kingdom
Match confidence
60%
Source feed
ClinicalTrials.gov
Automated source synopsis

A registered PHASE4 study indexed because it matched monitored longevity research terms. Registry status: Completed. Registration does not establish safety or effectiveness.

Evidence snapshot

What the source actually supports

Evidence stage
Phase 4
Study design
NA · SINGLE GROUP · TREATMENT · NONE
Evidence population
Human clinical study registration
Participants
103
Population
ALL · 50 Years
Duration
2014-08-28 to 2017-09-14
Intervention
Ranibizumab
Comparator
Not reported
Outcomes measured
Change in Central Subfield Retinal Thickness (CSRT) From Baseline to Day 90. — Baseline and Day 90; Change in Subfoveal Retinal Thickness (SRT) From Baseline to Day 180 — Baseline and Day 180; Change in Central Subfield Retinal Thickness (CSRT) From Baseline to Day 180 — Baseline and Day 180; Change in Central Subfield Retinal Volume (CSRV) From Baseline to Day 180 — Baseline and Day 180; Number of Patients With Intraretinal Fluid Assessed at Baseline and Day 180 — Baseline and Day 180; Number of Patients With Subretinal Fluid Assessed at Baseline and Day 180 — Baseline to Day 180; Number of Patients With Intraretinal/Subretinal Fluid Within the Central Subfield Fluid Assessed at Baseline and Day 18…; Number of Patients With Pigment Epithelial Detachments Assessed at Baseline and Day 180 — Baseline and Day 180; Number of Patients With Dry Retina Assessed at Baseline and Day 180 — Baseline and Day 180; Change in Maximum PED Height From Baseline to Day 180 — Baseline and Day 180; Change in Maximum PED Diameter From Baseline to Day 180 — Baseline and Day 180; Change in Maximum IRC Height From Baseline to Day 180 — Baseline and Day 180; Change in Best Corrected Visual Acuity (BCVA) in the Study Eye — Baseline, Day 90 and Day 180; Change in ETDRS Letters for Study Eye From Baseline to Day 180 — Baseline and Day 180; Incidence of Ocular TEAEs in the Study Eye Reported by ≥2% Patients From Baseline to Day 180 — Baseline to Day 180
Reported result
No reusable finding-level result is available in this record.

Main limitationThis is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.

Safety and approvalEligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians. Trial registration is not regulatory approval and does not establish that an intervention is available.

Source supportStructured registry protocol metadata; no finding-level conclusion is generated.

Trial stage · Phase 4A trial phase describes development stage; it does not establish a positive result.
Phase 1Phase 2Phase 3Phase 4

Registration and recruitment status do not establish safety, efficacy, or regulatory approval.

Why this record appears here · 60% topic match

The title, summary, or source keywords matched one or more topics followed by immortal.life. A higher percentage means a stronger topic match; it does not rate safety, effectiveness, or study quality.

  • Vision ageing · 60%Source terminology contains a controlled topic term. Source terminology supplies ageing or longevity context.

Automated source check 100% · update recency 50%. These figures help sort records; they are not medical ratings.