Clinical trial registry record

First-in-Human Study of LHA510 in Elderly Subjects and Patients With Age-Related Macular Degeneration

A registered PHASE1 study indexed because it matched monitored longevity research terms. Registry status: Completed. Registration does not establish safety or effectiveness.

Plain-language guide

Five questions to ask about this record

What this is
A clinical study registration, not a result or recommendation.
Why it may matter
The registry currently reports Completed.
Evidence
Registered phase 1 study.
Main limitation
Registration does not prove that the intervention works, is safe, or is available to you.
What changed
Registry metadata was last updated April 1, 2016.
Where to verify
Open the primary registry below for eligibility, locations, contacts, and current status.
Registry ID
NCT02076919
Last registry update
April 1, 2016
Status
Completed
Phase
Phase 1
Sponsor
Alcon Research
Enrollment
110
Match confidence
100%
Source feed
ClinicalTrials.gov
Automated source synopsis

A registered PHASE1 study indexed because it matched monitored longevity research terms. Registry status: Completed. Registration does not establish safety or effectiveness.

Evidence snapshot

What the source actually supports

Evidence stage
Phase 1
Study design
RANDOMIZED · PARALLEL · BASIC SCIENCE · DOUBLE
Evidence population
Human clinical study registration
Participants
110
Population
ALL · 55 Years to 80 Years
Duration
2014-02-01 to 2014-06-01
Intervention
LHA510 Ophthalmic Suspension; LHA510 Vehicle
Comparator
LHA510 Vehicle Part 1; LHA510 Vehicle Part 2
Outcomes measured
Number of Subjects With a Serious Adverse Event That, in the Opinion of the Investigator, is Related to the Study Drug,…; Number of Subjects Experiencing a Non-serious Adverse Event, Part I — From time of consent until 30 days after stopping…; Number of Subjects Experiencing a Non-serious Adverse Event, Part 2 — From time of consent until 30 days after stopping…; The Observed Maximum Plasma (or Serum or Blood) Concentration Following Drug Administration [Mass / Volume] (Cmax), Par…; The Time to Reach the Maximum Concentration After Drug Administration [Time] (Tmax), Part 2 — Up to Day 15; The Area Under the Plasma (or Serum or Blood) Concentration-time Curve From Time Zero to the Time of the Last Quantifia…; The Terminal Elimination Half-life [Time] (T1/2), Part 2 — Up to Day 15; Change From Baseline in Diastolic Blood Pressure at Each Post Dose Timepoint, Part 1 — Day 1: 0.25h, 0.5h, 1h, 2h, 4h,…; Change From Baseline in Systolic Blood Pressure at Each Post Dose Timepoint, Part 1 — Day 1: 0.25h, 0.5h, 1h, 2h, 4h, 6…; Change From Baseline in Mean Arterial Blood Pressure at Each Post Dose Timepoint, Part 1 — Day 1: 0.25h, 0.5h, 1h, 2h,…; Change From Baseline in Diastolic Blood Pressure at Each Post Dose Timepoint, Part 2 — Day 1 and 7: 0.25h, 0.5h, 1h, 2h…; Change From Baseline in Systolic Blood Pressure at Each Post Dose Timepoint, Part 2 — Day 1 and 7: 0.25h, 0.5h, 1h, 2h,…; Change From Mean Arterial Blood Pressure at Each Post Dose Timepoint, Part 2 — Day 1 and 7: 0.25h, 0.5h, 1h, 2h, 4h, 6h…
Reported result
No reusable finding-level result is available in this record.

Main limitationThis is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.

Safety and approvalEligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians. Trial registration is not regulatory approval and does not establish that an intervention is available.

Source supportStructured registry protocol metadata; no finding-level conclusion is generated.

Trial stage · Phase 1A trial phase describes development stage; it does not establish a positive result.
Phase 1Phase 2Phase 3Phase 4

Registration and recruitment status do not establish safety, efficacy, or regulatory approval.

Why this record appears here · 100% topic match

The title, summary, or source keywords matched one or more topics followed by immortal.life. A higher percentage means a stronger topic match; it does not rate safety, effectiveness, or study quality.

  • Vision ageing · 100%Title contains controlled topic terminology. Source terminology contains a controlled topic term. Title supplies ageing or longevity context.

Automated source check 100% · update recency 35%. These figures help sort records; they are not medical ratings.