Clinical trial registry record

Evaluation of Wet Age-Related Macular Degeneration (AMD) Genetic Profile Interactions With Ranibizumab Treatment Outcomes

A registered study indexed because it matched monitored longevity research terms. Registry status: Completed. Registration does not establish safety or effectiveness.

Plain-language guide

Five questions to ask about this record

What this is
A clinical study registration, not a result or recommendation.
Why it may matter
The registry currently reports Completed.
Evidence
Registered phase not reported study.
Main limitation
Registration does not prove that the intervention works, is safe, or is available to you.
What changed
Registry metadata was last updated March 17, 2016.
Where to verify
Open the primary registry below for eligibility, locations, contacts, and current status.
Registry ID
NCT01363570
Last registry update
March 17, 2016
Status
Completed
Phase
Phase not reported
Sponsor
McMaster University
Enrollment
70
Countries
Canada
Match confidence
80%
Source feed
ClinicalTrials.gov
Automated source synopsis

A registered study indexed because it matched monitored longevity research terms. Registry status: Completed. Registration does not establish safety or effectiveness.

Evidence snapshot

What the source actually supports

Evidence stage
Phase not reported
Study design
NA · SINGLE GROUP · TREATMENT · NONE
Evidence population
Human clinical study registration
Participants
70
Population
ALL · 18 Years to 99 Years
Duration
2012-01-01 to 2014-10-01
Intervention
Ranibizumab
Comparator
Not reported
Outcomes measured
Gains in visual acuity — Baseline and months 1, 2, 3, 4, 5, and 6; Changes in choroid vessel activity in lesion growth and activity at choroid — Baseline and months 1, 2, 3, 4, 5 and 6; Rate of cataract progression — Baseline and months 1, 2, 3, 4, 5, and 6; Resolution of macular edema — Baseline and months 1, 2, 3, 4, 5, 6; Mean change in visual acuity according to identified genetic mutations — Baseline and Months 1, 2, 3, 4, 5, 6; Mean change in visual acuity regardless of genetic profile results — Baseline and Months 1, 2, 3, 4, 5, 6; Interaction of smoking status and genetic profile on visual acuity changes — Baseline and Months 1, 2, 3, 4, 5, 6
Reported result
No reusable finding-level result is available in this record.

Main limitationThis is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.

Safety and approvalEligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians. Trial registration is not regulatory approval and does not establish that an intervention is available.

Source supportStructured registry protocol metadata; no finding-level conclusion is generated.

Trial stage · Phase not reportedA trial phase describes development stage; it does not establish a positive result.
Phase 1Phase 2Phase 3Phase 4

Registration and recruitment status do not establish safety, efficacy, or regulatory approval.

Why this record appears here · 80% topic match

The title, summary, or source keywords matched one or more topics followed by immortal.life. A higher percentage means a stronger topic match; it does not rate safety, effectiveness, or study quality.

  • Vision ageing · 80%Title contains controlled topic terminology. Title supplies ageing or longevity context.

Automated source check 100% · update recency 35%. These figures help sort records; they are not medical ratings.

vision aging
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