Clinical trial registry record

Improving Vaccination in Older Adults by Inducing Autophagy With Spermidine

A registered study indexed because it matched monitored longevity research terms. Registry status: Completed. Registration does not establish safety or effectiveness.

Plain-language guide

Five questions to ask about this record

What this is
A clinical study registration, not a result or recommendation.
Why it may matter
The registry currently reports Completed.
Evidence
Registered phase not reported study.
Main limitation
Registration does not prove that the intervention works, is safe, or is available to you.
What changed
Registry metadata was last updated May 9, 2024.
Where to verify
Open the primary registry below for eligibility, locations, contacts, and current status.
Registry ID
NCT05421546
Last registry update
May 9, 2024
Status
Completed
Phase
Phase not reported
Sponsor
University of Oxford
Enrollment
40
Countries
United Kingdom
Match confidence
100%
Source feed
ClinicalTrials.gov
Automated source synopsis

A registered study indexed because it matched monitored longevity research terms. Registry status: Completed. Registration does not establish safety or effectiveness.

Evidence snapshot

What the source actually supports

Evidence stage
Phase not reported
Study design
RANDOMIZED · PARALLEL · BASIC SCIENCE · TRIPLE
Evidence population
Human clinical study registration
Participants
40
Population
ALL · 65 Years to 90 Years
Duration
2022-08-01 to 2023-12-02
Intervention
Spermidine or Placebo
Comparator
Spermidine arm; Placebo arm
Outcomes measured
The primary objective of this study is to determine the safety of daily Spermidine supplements following the vaccine bo…; Our secondary objective is to determine the effects of daily Spermidine supplements on the immune 'memory' response to…
Reported result
No reusable finding-level result is available in this record.

Main limitationThis is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.

Safety and approvalEligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians. Trial registration is not regulatory approval and does not establish that an intervention is available.

Source supportStructured registry protocol metadata; no finding-level conclusion is generated.

Trial stage · Phase not reportedA trial phase describes development stage; it does not establish a positive result.
Phase 1Phase 2Phase 3Phase 4

Registration and recruitment status do not establish safety, efficacy, or regulatory approval.

Why this record appears here · 100% topic match

The title, summary, or source keywords matched one or more topics followed by immortal.life. A higher percentage means a stronger topic match; it does not rate safety, effectiveness, or study quality.

  • Autophagy · 100%Title contains controlled term: autophagy. Abstract contains controlled term: autophagy. Title supplies longevity context: older adult. Study type is explicitly identified as INTERVENTIONAL.
  • Spermidine · 100%Title contains controlled term: spermidine. Abstract contains controlled term: spermidine. Source terminology contains: spermidine. Title supplies longevity context: older adult. Study type is explicitly identified as INTERVENTIONAL.

Automated source check 100% · update recency 65%. These figures help sort records; they are not medical ratings.

autophagyspermidine
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