A registered study indexed because it matched monitored longevity research terms. Registry status: Recruiting. Registration does not establish safety or effectiveness.
What the source actually supports
- Evidence stage
- Phase not reported
- Study design
- RANDOMIZED · PARALLEL · OTHER · QUADRUPLE
- Evidence population
- Human clinical study registration
- Participants
- 126
- Population
- ALL · 50 Years to 70 Years
- Duration
- 2025-06-05 to 2027-03-31
- Intervention
- NMN; Placebo
- Comparator
- Placebo Arm
- Outcomes measured
- CD3+CD8+CD27-CD28- T cells as a percentage of CD3+CD8+ T cells, expressed in %, evaluated by flow cytometry — 26 weeks; Body composition analysis, expressed in kg, %, and g/cm², evaluated by dual-energy X-ray absorptiometry — 26 weeks; Determination of fasting blood glucose and OGTT 2-hour blood glucose, expressed in mmol/L, evaluated by glucose oxidase…; CD3+CD8+CD27- T cells as a percentage of total CD3+CD8+ T cells, expressed in %, evaluated by flow cytometry — 26 weeks; CD3+CD8+CD28- T cells as a percentage of total CD3+CD8+ T cells, expressed in %, evaluated by flow cytometry — 26 weeks; CD3+CD4+CD27- T cells as a percentage of CD3+CD4+ T cells, expressed in %, evaluated by flow cytometry — 26 weeks; CD3+CD4+CD28- T cells as a percentage of CD3+CD4+ T cells, expressed in %, evaluated by flow cytometry — 26 weeks; CD3+CD4+CD27-CD28- T cells as a percentage of CD3+CD4+ T cells, expressed in %, evaluated by flow cytometry — 26 weeks; CD3+CD8+CD45RA+CCR7- T cells as a percentage of CD3+CD8+ T cells, expressed in %, evaluated by flow cytometry — 26 weeks; CD3+CD8+CD57+KLRG1+ T cells as a percentage of CD3+CD8+ T cells, expressed in %, evaluated by flow cytometry — 26 weeks; CD3+CD8+ T cells as a percentage of CD3+CD4+ T cells, expressed in %, evaluated by flow cytometry — 26 weeks; NMN, NAD+ levels in peripheral blood cells, evaluated by mass spectrometry — 26 weeks; Peripheral blood cell telomere length, expressed as a unitless value , evaluated by Quantitative Real-time polymerase c…; Cardiorespiratory fitness related indicators, expressed in mL/kg/min, L/min, beats/min, and unitless ratios, evaluated…; Glycosylated hemoglobin, expressed in mmol/mol, evaluated by HPLC — 26 weeks; Pancreatic β-cell function, expressed as a unitless value, evaluated by HOMA-β、HOMA-IR — 26 weeks; Weight, expressed in kilograms, evaluated by weighing scale — 26 weeks; Waist circumference, expressed in centimeters, evaluated by tape measure — 26 weeks; Waist-to-hip ratio, expressed as a unitless ratio, evaluated using a standardized tape measure following WHO measuremen…; Waist-to-height, expressed as a unitless ratio, evaluated using a standardized tape measure following WHO measurement p…
- Reported result
- No reusable finding-level result is available in this record.
Main limitationThis is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.
Safety and approvalEligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians. Trial registration is not regulatory approval and does not establish that an intervention is available.
Source supportStructured registry protocol metadata; no finding-level conclusion is generated.
Registration and recruitment status do not establish safety, efficacy, or regulatory approval.
Why this record appears here · 100% topic match
The title, summary, or source keywords matched one or more topics followed by immortal.life. A higher percentage means a stronger topic match; it does not rate safety, effectiveness, or study quality.
- Immune ageing · 100%Title contains controlled term: immunosenescence. Abstract contains controlled term: immunosenescence. Source terminology contains: immunosenescence. Title supplies longevity context: senescence, elderly. Study type is explicitly identified as INTERVENTIONAL.
- NAD metabolism · 100%Title contains controlled term: nicotinamide mononucleotide. Abstract contains controlled term: nicotinamide mononucleotide, nmn. Source terminology contains: nmn. Title supplies longevity context: senescence, elderly. Study type is explicitly identified as INTERVENTIONAL.
Automated source check 100% · update recency 65%. These figures help sort records; they are not medical ratings.