Clinical trial registry record

Supplement and Exercise Effects on Stationary Immunity and Health in Older Adults

A registered study indexed because it matched monitored longevity research terms. Registry status: Recruiting. Registration does not establish safety or effectiveness.

Plain-language guide

Five questions to ask about this record

What this is
A clinical study registration, not a result or recommendation.
Why it may matter
The registry currently reports Recruiting.
Evidence
Registered phase not reported study.
Main limitation
Registration does not prove that the intervention works, is safe, or is available to you.
What changed
Registry metadata was last updated December 22, 2025.
Where to verify
Open the primary registry below for eligibility, locations, contacts, and current status.
Registry ID
NCT07251244
Last registry update
December 22, 2025
Status
Recruiting
Phase
Phase not reported
Sponsor
University of Valencia
Enrollment
60
Countries
Spain
Match confidence
100%
Source feed
ClinicalTrials.gov
Automated source synopsis

A registered study indexed because it matched monitored longevity research terms. Registry status: Recruiting. Registration does not establish safety or effectiveness.

Evidence snapshot

What the source actually supports

Evidence stage
Phase not reported
Study design
RANDOMIZED · PARALLEL · PREVENTION · TRIPLE
Evidence population
Human clinical study registration
Participants
60
Population
ALL · 65 Years
Duration
2025-12-15 to 2026-07-01
Intervention
Group 1: Exercise + nutritional supplement (EXNS); Group 2: Exercise + placebo nutritional supplement (EXPlaNS)
Comparator
Group 2: Exercise + placebo nutritional supplement (EXPlaNS)
Outcomes measured
Changes in inteleukin 6 (IL-6) — Pre-, mid-, and post-intervention of 6 months; Changes in tumor necrosis factor alfa (TNF-α) — Pre-, mid-, and post-intervention of 6 months; Changes in immunoglobulin A and G (IgA, IgG) — Pre-, mid-, and post-intervention of 6 months; Change in high-sensitivity C-reactive protein (hs-CRP) — Pre-, mid-, and post-intervention of 6 months; Complete blood count with leukocyte differential for neutrophil-to-lymphocyte ratio (NLR) calculation — Pre-, mid-, and…; Changes in interferon gamma (IFN-γ) — Pre-, mid-, and post-intervention of 6 months; Change in F2-isoprostanes — Pre-, mid-, and post-intervention of 6 months; Change in reduced glutathione (GSH) — Pre-, mid-, and post-intervention of 6 months; Change in total antioxidant capacity (TAC) — Pre-, mid-, and post-intervention of 6 months; Change in quality of life — Pre-, mid-, and post-intervention of 6 months; Change in general health perception — Pre-, mid-, and post-intervention of 6 months; Change in gastrointestinal symptoms and gut health — Pre-, mid-, and post-intervention of 6 months; Change in frequency and duration of minor illnesses — Pre-, mid-, and post-intervention of 6 months; Adherence to supplement and exercise — Every day for nutritional supplement and each exercise session during the 6 mont…; Satisfaction with the intervention — Mid- and post-intervention of 6 months; Change in distance covered/aerobic capacity — Pre-, mid-, and post-intervention of 6 months; Changes in lower limb strength — Pre-, mid-, and post-intervention of 6 months; Changes in agility and dynamic balance — Pre-, mid-, and post-intervention of 6 months; Changes in handgrip strength — Pre-, mid-, and post-intervention of 6 months; Changes in resting heart rate and blood pressure — Pre-, mid-, and post-intervention of 6 months
Reported result
No reusable finding-level result is available in this record.

Main limitationThis is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.

Safety and approvalEligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians. Trial registration is not regulatory approval and does not establish that an intervention is available.

Source supportStructured registry protocol metadata; no finding-level conclusion is generated.

Trial stage · Phase not reportedA trial phase describes development stage; it does not establish a positive result.
Phase 1Phase 2Phase 3Phase 4

Registration and recruitment status do not establish safety, efficacy, or regulatory approval.

Why this record appears here · 100% topic match

The title, summary, or source keywords matched one or more topics followed by immortal.life. A higher percentage means a stronger topic match; it does not rate safety, effectiveness, or study quality.

  • Exercise · 100%Title contains controlled term: exercise. Abstract contains controlled term: exercise. Source terminology contains: exercise. Title supplies longevity context: older adult. Study type is explicitly identified as INTERVENTIONAL.

Automated source check 100% · update recency 85%. These figures help sort records; they are not medical ratings.