A registered PHASE2 study indexed because it matched monitored longevity research terms. Registry status: Not Yet Recruiting. Registration does not establish safety or effectiveness.
What the source actually supports
- Evidence stage
- Phase 2
- Study design
- RANDOMIZED · PARALLEL · PREVENTION · QUADRUPLE
- Evidence population
- Human clinical study registration
- Participants
- 90
- Population
- ALL · 65 Years to 85 Years
- Duration
- 2026-12-01 to 2030-11-01
- Intervention
- Calcium-HMB Plus Vitamin D3; Matching placebo
- Comparator
- Matching Placebo
- Outcomes measured
- Change in Appendicular Lean Mass — Baseline to month 6; Title Change in Body Weight — Baseline to month 6; Change in Total Fat Mass — Baseline to month 6; Title Change in Visceral Adipose Tissue — Baseline to month 6; Change in Bone Mineral Density — Baseline to month 6; Change in Trabecular Bone Score — Baseline to month 6; Change in Glycated Hemoglobin — Time Frame Baseline to month 6; Change in Fasting Plasma Glucose — Baseline to month 6; Change in Resting Metabolic Rate — Baseline to month 6; Change in Handgrip Strength — Baseline, month 3, and month 6; Title Change in Lower-Extremity Strength or Torque — Baseline to month 6; Title Change in Short Physical Performance Battery Score — Baseline, month 3, and month 6; Change in Six-Minute Walk Distance — Baseline, month 3, and month 6; Change in Gait Measures — Baseline, month 3, and month 6; Change in Physical Activity — Protocol-defined monitoring periods at baseline or month 3 and month 6; Change in Whole-Body CT-Derived Muscle Volume and Composition — Baseline to month 6; Change in Total Body Creatine Pool Size — Baseline to month 6; Change in Myofibrillar Protein Synthesis — Baseline and month 6 Aim 3 metabolic visits; Change in Muscle Protein Breakdown — Baseline and month 6 Aim 3 metabolic visits; Change in Net Muscle Protein Balance — Baseline and month 6 Aim 3 metabolic visits
- Reported result
- No reusable finding-level result is available in this record.
Main limitationThis is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.
Safety and approvalEligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians. Trial registration is not regulatory approval and does not establish that an intervention is available.
Source supportStructured registry protocol metadata; no finding-level conclusion is generated.
Registration and recruitment status do not establish safety, efficacy, or regulatory approval.
Why this record appears here · 100% topic match
The title, summary, or source keywords matched one or more topics followed by immortal.life. A higher percentage means a stronger topic match; it does not rate safety, effectiveness, or study quality.
- GLP-1 therapies · 100%Title contains controlled topic terminology. Summary contains controlled topic terminology. Title supplies ageing or longevity context.
- Vitamin D and ageing · 100%Title contains controlled topic terminology. Summary contains controlled topic terminology. Source terminology contains a controlled topic term. Title supplies ageing or longevity context.
Automated source check 100% · update recency 100%. These figures help sort records; they are not medical ratings.