Clinical trial registry record

Effects of Specific Amino Acid Supplementation and Lifestyle Factors on Brain Ageing

A registered study indexed because it matched monitored longevity research terms. Registry status: Recruiting. Registration does not establish safety or effectiveness.

Plain-language guide

Five questions to ask about this record

What this is
A clinical study registration, not a result or recommendation.
Why it may matter
The registry currently reports Recruiting.
Evidence
Registered phase not reported study.
Main limitation
Registration does not prove that the intervention works, is safe, or is available to you.
What changed
Registry metadata was last updated March 27, 2026.
Where to verify
Open the primary registry below for eligibility, locations, contacts, and current status.
Registry ID
NCT07497347
Last registry update
March 27, 2026
Status
Recruiting
Phase
Phase not reported
Sponsor
IRCCS Centro San Giovanni di Dio Fatebenefratelli
Enrollment
84
Countries
Italy
Match confidence
80%
Source feed
ClinicalTrials.gov
Automated source synopsis

A registered study indexed because it matched monitored longevity research terms. Registry status: Recruiting. Registration does not establish safety or effectiveness.

Evidence snapshot

What the source actually supports

Evidence stage
Phase not reported
Study design
RANDOMIZED · PARALLEL · SUPPORTIVE CARE · DOUBLE
Evidence population
Human clinical study registration
Participants
84
Population
ALL · 65 Years to 85 Years
Duration
2026-03-01 to 2029-02-01
Intervention
L-serine supplementation; Placebo
Comparator
Placebo group
Outcomes measured
Geriatric Depression Scale - 15 — Baseline; week 18; week 48 (end of the trial); Repeatable Battery for the Assessment of Neuropsychological Status — Baseline, Week 18; Week 48 (end of the trial); Patient Health Questionnaire - 9 — Baseline; Week 18; Week 48 (end of the trial); Montgomery-Åsberg Depression Rating Scale — Baseline, Week 18; Week 48 (end of the trial); World Health Organization Quality of Life - Bref — Baseline, Week 18, Week 48 (end of trial); Electroencephalogram -derived neurophysiological metrics — Baseline, Week 48 (end of the trial); Gut Microbiome Composition — Baseline, Week 18; Week 48 (end of trial); Immune-related biomarkers levels — Baseline; Week 18; Week 48 (end of trial); Amino acid and metabolic biomarkers — Baseline, Week 18; Week 48 (end of trial); Neuroendocrine and stress-related biomarkers — Baseline, Week 18; Week 48; Neurotrophic biomarkers — Baseline, Week 18; Week 48
Reported result
No reusable finding-level result is available in this record.

Main limitationThis is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.

Safety and approvalEligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians. Trial registration is not regulatory approval and does not establish that an intervention is available.

Source supportStructured registry protocol metadata; no finding-level conclusion is generated.

Trial stage · Phase not reportedA trial phase describes development stage; it does not establish a positive result.
Phase 1Phase 2Phase 3Phase 4

Registration and recruitment status do not establish safety, efficacy, or regulatory approval.

Why this record appears here · 80% topic match

The title, summary, or source keywords matched one or more topics followed by immortal.life. A higher percentage means a stronger topic match; it does not rate safety, effectiveness, or study quality.

  • Cognitive ageing · 80%Title contains controlled term: brain ageing. Title supplies longevity context: ageing. Study type is explicitly identified as INTERVENTIONAL.

Automated source check 100% · update recency 85%. These figures help sort records; they are not medical ratings.

cognitive aging
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