Clinical trial registry record

Low-intensity Hippocampal Transcranial Ultrasound Stimulation for Managing Cognitive and Sleep Dysfunction in Preclinical Alzheimer's Disease

A registered study indexed because it matched monitored longevity research terms. Registry status: Enrolling By Invitation. Registration does not establish safety or effectiveness.

Plain-language guide

Five questions to ask about this record

What this is
A clinical study registration, not a result or recommendation.
Why it may matter
The registry currently reports Enrolling By Invitation.
Evidence
Registered phase not reported study.
Main limitation
Registration does not prove that the intervention works, is safe, or is available to you.
What changed
Registry metadata was last updated December 23, 2025.
Where to verify
Open the primary registry below for eligibility, locations, contacts, and current status.
Registry ID
NCT07298876
Last registry update
December 23, 2025
Status
Enrolling By Invitation
Phase
Phase not reported
Sponsor
Chinese University of Hong Kong
Enrollment
20
Countries
Hong Kong
Match confidence
100%
Source feed
ClinicalTrials.gov
Automated source synopsis

A registered study indexed because it matched monitored longevity research terms. Registry status: Enrolling By Invitation. Registration does not establish safety or effectiveness.

Evidence snapshot

What the source actually supports

Evidence stage
Phase not reported
Study design
RANDOMIZED · FACTORIAL · TREATMENT · TRIPLE
Evidence population
Human clinical study registration
Participants
20
Population
ALL · 60 Years to 85 Years
Duration
2026-04-01 to 2027-05-16
Intervention
Low-intensity transcranial ultrasound stimulation; Sham low-intensity transcranial ultrasound stimulation
Comparator
Active TUS
Outcomes measured
Pittsburg Sleep Quality Index (PSQI) — 10 weeks; Delayed recall of the words — 10 weeks; Objective sleep quality — 2 weeks; The levels of plasma Aß — 10 weeks; The levels of plasma tau — 10 weeks
Reported result
No reusable finding-level result is available in this record.

Main limitationThis is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.

Safety and approvalEligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians. Trial registration is not regulatory approval and does not establish that an intervention is available.

Source supportStructured registry protocol metadata; no finding-level conclusion is generated.

Trial stage · Phase not reportedA trial phase describes development stage; it does not establish a positive result.
Phase 1Phase 2Phase 3Phase 4

Registration and recruitment status do not establish safety, efficacy, or regulatory approval.

Why this record appears here · 100% topic match

The title, summary, or source keywords matched one or more topics followed by immortal.life. A higher percentage means a stronger topic match; it does not rate safety, effectiveness, or study quality.

  • Sleep · 100%Title contains controlled term: sleep. Abstract contains controlled term: sleep. Source terminology contains: sleep. Title supplies longevity context: aging. Study type is explicitly identified as INTERVENTIONAL.

Automated source check 100% · update recency 85%. These figures help sort records; they are not medical ratings.

sleep
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