Clinical trial registry record

Modulating Surgery-Induced Blood-Brain Barrier Disruption in Elderly

A registered study indexed because it matched monitored longevity research terms. Registry status: Unknown. Registration does not establish safety or effectiveness.

Plain-language guide

Five questions to ask about this record

What this is
A clinical study registration, not a result or recommendation.
Why it may matter
The registry currently reports Unknown.
Evidence
Registered phase not reported study.
Main limitation
Registration does not prove that the intervention works, is safe, or is available to you.
What changed
Registry metadata was last updated April 17, 2024.
Where to verify
Open the primary registry below for eligibility, locations, contacts, and current status.
Registry ID
NCT06090955
Last registry update
April 17, 2024
Status
Unknown
Phase
Phase not reported
Sponsor
Samsung Medical Center
Enrollment
108
Countries
South Korea
Match confidence
100%
Source feed
ClinicalTrials.gov
Automated source synopsis

A registered study indexed because it matched monitored longevity research terms. Registry status: Unknown. Registration does not establish safety or effectiveness.

Evidence snapshot

What the source actually supports

Evidence stage
Phase not reported
Study design
RANDOMIZED · PARALLEL · PREVENTION · QUADRUPLE
Evidence population
Human clinical study registration
Participants
108
Population
ALL · 65 Years
Duration
2023-10-25 to 2024-12-31
Intervention
Dexmedetomidine Injection [Precedex]; Lidocaine IV; normal saline
Comparator
Control group
Outcomes measured
Postoperative change of cerebrospinal-plasma albumin ratio (CPAR) — From the baseline to immediate postoperative values; The changes of inflammatory biomarker level in blood — From the baseline to immediate postoperative state and postopera…; The changes of neuronal damage biomarker level in blood — From the baseline to immediate postoperative state and postop…; The changes of inflammatory, neuronal damage, BBB permeability biomarker level in blood — From the baseline to immediat…; The incidence of postoperative delirium — From postoperative day 0 to 5; The subtype of postoperative delirium — From postoperative day 0 to 5; Delirium Rating Scale Revised (DRS-R-98) — From postoperative day 0 to 5; Onset and duration of delirium — From postoperative day 0 to 5; Pain score (NRS) — From postoperative day 0 to 5; Subjective sleep quality — From postoperative day 0 to 5; Montreal cognitive Assessment (MoCA) — at baseline and 7 days after surgery or at discharge; Ideal outcome of pancreatoduodenectmoy — postoperative day 30; non-delirium complications within 30 days after surgery — Within 30 days after surgery
Reported result
No reusable finding-level result is available in this record.

Main limitationThis is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.

Safety and approvalEligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians. Trial registration is not regulatory approval and does not establish that an intervention is available.

Source supportStructured registry protocol metadata; no finding-level conclusion is generated.

Trial stage · Phase not reportedA trial phase describes development stage; it does not establish a positive result.
Phase 1Phase 2Phase 3Phase 4

Registration and recruitment status do not establish safety, efficacy, or regulatory approval.

Why this record appears here · 100% topic match

The title, summary, or source keywords matched one or more topics followed by immortal.life. A higher percentage means a stronger topic match; it does not rate safety, effectiveness, or study quality.

  • Blood-brain barrier ageing · 100%Title contains controlled term: blood-brain barrier. Abstract contains controlled term: blood-brain barrier. Title supplies longevity context: elderly. Study type is explicitly identified as INTERVENTIONAL.

Automated source check 100% · update recency 65%. These figures help sort records; they are not medical ratings.