Clinical trial registry record

Probiotic Intervention on Gut Microbiota and Cognitive Functioning in Older Adults With a Mild Cognitive Impairment

A registered study indexed because it matched monitored longevity research terms. Registry status: Unknown. Registration does not establish safety or effectiveness.

Plain-language guide

Five questions to ask about this record

What this is
A clinical study registration, not a result or recommendation.
Why it may matter
The registry currently reports Unknown.
Evidence
Registered phase not reported study.
Main limitation
Registration does not prove that the intervention works, is safe, or is available to you.
What changed
Registry metadata was last updated May 15, 2023.
Where to verify
Open the primary registry below for eligibility, locations, contacts, and current status.
Registry ID
NCT05859230
Last registry update
May 15, 2023
Status
Unknown
Phase
Phase not reported
Sponsor
National University of Singapore
Enrollment
50
Countries
Singapore
Match confidence
100%
Source feed
ClinicalTrials.gov
Automated source synopsis

A registered study indexed because it matched monitored longevity research terms. Registry status: Unknown. Registration does not establish safety or effectiveness.

Evidence snapshot

What the source actually supports

Evidence stage
Phase not reported
Study design
RANDOMIZED · PARALLEL · PREVENTION · QUADRUPLE
Evidence population
Human clinical study registration
Participants
50
Population
ALL · 60 Years to 90 Years
Duration
2022-08-05 to 2023-12-01
Intervention
Experimental: The probiotic drink study group; Placebo Comparator: The placebo drink study group
Comparator
The placebo drink study group
Outcomes measured
Change in composition of gut microbiota after probiotic and placebo intervention — Baseline, 6 weeks, 12 weeks of inter…; Changes in verbal learning and memory function of neurocognitive assessment after probiotic and placebo intervention —…; Changes in attention and verbal working memory function of neurocognitive assessment after probiotic and placebo interv…; Changes in sustained attention and reasoning function by color trails neurocognitive assessment after probiotic and pla…; Changes in sustained attention and reasoning function by Stroop test of neurocognitive assessment after probiotic and p…; Changes in language, lexical knowledge and semantic memory function of neurocognitive assessment after probiotic and pl…; Changes in visuospatial, organizational non-verbal processing function of neurocognitive assessment after probiotic and…; Changes in plasma immune and inflammatory markers after probiotic and placebo intervention — Baseline, 6 weeks, 12 week…; Changes in blood immune and inflammatory markers in-vitro stimulation by toll-like receptors agonists after probiotic a…; Changes in blood cortisol levels after probiotic and placebo intervention — Baseline, 6 weeks, 12 weeks of intervention…; Changes in fecal short-chain fatty acids after probiotic and placebo intervention — Baseline, 6 weeks, 12 weeks of inte…
Reported result
No reusable finding-level result is available in this record.

Main limitationThis is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.

Safety and approvalEligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians. Trial registration is not regulatory approval and does not establish that an intervention is available.

Source supportStructured registry protocol metadata; no finding-level conclusion is generated.

Trial stage · Phase not reportedA trial phase describes development stage; it does not establish a positive result.
Phase 1Phase 2Phase 3Phase 4

Registration and recruitment status do not establish safety, efficacy, or regulatory approval.

Why this record appears here · 100% topic match

The title, summary, or source keywords matched one or more topics followed by immortal.life. A higher percentage means a stronger topic match; it does not rate safety, effectiveness, or study quality.

  • Microbiome and dysbiosis · 100%Title contains controlled term: gut microbiota. Abstract contains controlled term: gut microbiota. Title supplies longevity context: older adult. Study type is explicitly identified as INTERVENTIONAL.

Automated source check 100% · update recency 50%. These figures help sort records; they are not medical ratings.

microbiome dysbiosis
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