Clinical trial registry record

A Study to Assess the Efficacy and Safety of RO7965032 in Participants With Geographic Atrophy Secondary to Age-Related Macular Degeneration

A registered PHASE2 study indexed because it matched monitored longevity research terms. Registry status: Not Yet Recruiting. Registration does not establish safety or effectiveness.

Plain-language guide

Five questions to ask about this record

What this is
A clinical study registration, not a result or recommendation.
Why it may matter
The registry currently reports Not Yet Recruiting.
Evidence
Registered phase 2 study.
Main limitation
Registration does not prove that the intervention works, is safe, or is available to you.
What changed
Registry metadata was last updated October 1, 2026.
Where to verify
Open the primary registry below for eligibility, locations, contacts, and current status.
Registry ID
NCT07851259
Last registry update
October 1, 2026
Status
Not Yet Recruiting
Phase
Phase 2
Sponsor
Genentech, Inc.
Enrollment
321
Match confidence
100%
Source feed
ClinicalTrials.gov
Automated source synopsis

A registered PHASE2 study indexed because it matched monitored longevity research terms. Registry status: Not Yet Recruiting. Registration does not establish safety or effectiveness.

Evidence snapshot

What the source actually supports

Evidence stage
Phase 2
Study design
RANDOMIZED · PARALLEL · TREATMENT · DOUBLE
Evidence population
Human clinical study registration
Participants
321
Population
ALL · 50 Years
Duration
2026-09-30 to 2030-08-21
Intervention
RO7965032; Placebo
Comparator
Placebo
Outcomes measured
Change of GA Lesion Area in the Study Eye — Baseline up to approximately 48 weeks; Incidence and Severity of Ocular Adverse Events (AEs) — Up to approximately 72 Weeks; Incidence and Severity of Non-Ocular AEs — Up to approximately 72 Weeks; Change of GA Lesion Area in the Study Eye — Baseline up to approximately 72 weeks; Change from Baseline in Best Correct Visual Acuity (BCVA) Score on the Early Treatment Diabetic Retinopathy Study (ETDR…; Change from Baseline in BCVA Score on the ETDRS Chart Under Low-luminance Conditions — Baseline up to approximately 48…; Incidence and Severity of Selected Findings in Ocular Examinations and Ocular Imaging — Up to approximately 72 Weeks; Plasma Concentration of RO7965032 — Baseline up to approximately 72 weeks; Percent Change from Baseline in Levels of Target Protein in Plasma — Baseline up to approximately 72 weeks; Percent Change from Baseline in Levels of Plasma Biomarker Activity — Baseline up to approximately 72 weeks; Prevalence and Incidence of Anti-Drug Antibodies (ADAs) — Baseline up to approximately 72 weeks; Recommended Dose of RO7965032 — Up to approximately 72 Weeks
Reported result
No reusable finding-level result is available in this record.

Main limitationThis is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.

Safety and approvalEligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians. Trial registration is not regulatory approval and does not establish that an intervention is available.

Source supportStructured registry protocol metadata; no finding-level conclusion is generated.

Trial stage · Phase 2A trial phase describes development stage; it does not establish a positive result.
Phase 1Phase 2Phase 3Phase 4

Registration and recruitment status do not establish safety, efficacy, or regulatory approval.

Why this record appears here · 100% topic match

The title, summary, or source keywords matched one or more topics followed by immortal.life. A higher percentage means a stronger topic match; it does not rate safety, effectiveness, or study quality.

  • Vision ageing · 100%Title contains controlled topic terminology. Summary contains controlled topic terminology. Source terminology contains a controlled topic term. Title supplies ageing or longevity context.

Automated source check 100% · update recency 100%. These figures help sort records; they are not medical ratings.