Clinical trial registry record

Pilot Study of Losartan and N-acetylcysteine as Inhibitors of Muscle Oxidative Stress in Elderly

A registered PHASE1, PHASE2 study indexed because it matched monitored longevity research terms. Registry status: Completed. Registration does not establish safety or effectiveness.

Plain-language guide

Five questions to ask about this record

What this is
A clinical study registration, not a result or recommendation.
Why it may matter
The registry currently reports Completed.
Evidence
Registered phase 1, phase 2 study.
Main limitation
Registration does not prove that the intervention works, is safe, or is available to you.
What changed
Registry metadata was last updated May 8, 2018.
Where to verify
Open the primary registry below for eligibility, locations, contacts, and current status.
Registry ID
NCT01384591
Last registry update
May 8, 2018
Status
Completed
Phase
Phase 1, Phase 2
Sponsor
The University of Texas Medical Branch, Galveston
Enrollment
6
Countries
United States
Match confidence
80%
Source feed
ClinicalTrials.gov
Automated source synopsis

A registered PHASE1, PHASE2 study indexed because it matched monitored longevity research terms. Registry status: Completed. Registration does not establish safety or effectiveness.

Evidence snapshot

What the source actually supports

Evidence stage
Phase 1, Phase 2
Study design
RANDOMIZED · PARALLEL · TREATMENT · QUADRUPLE
Evidence population
Human clinical study registration
Participants
6
Population
ALL · 60 Years to 85 Years
Duration
2011-07-01 to 2015-05-01
Intervention
N-acetylcysteine; Losartan; Placebo losartan; Placebo N-acetylcysteine
Comparator
Placebo losartan and placebo N-acetylcysteine
Outcomes measured
Leg Blood Flow as Measured by Doppler Ultrasound — Baseline; Leg Blood Flow as Measured by Doppler Ultrasound — 12 hours post dose one of the intervention; Leg Blood Flow as Measured by Doppler Ultrasound — 1 hour post dose two of the intervention, average of 13 hours post d…; Leg Blood Flow as Measured by Doppler Ultrasound — 2 hours post dose two of the intervention, average of 14 hours post…; Leg Blood Flow as Measured by Doppler Ultrasound — Post dose three of the intervention and a meal, average of 17 hours…; Leg Blood Flow as Measured by Doppler Ultrasound — 1 hour post dose three of the intervention and a meal, average of 18…; Leg Blood Flow as Measured by Doppler Ultrasound — 2 hours post dose three of the intervention and a meal, average of 1…; Handgrip Strength of Dominant Hand as Measured by Handgrip Dynamometry at 50% Perceived Effort at Baseline — baseline; Handgrip Strength of Non-dominant Hand as Measured by Handgrip Dynamometry at 50% Perceived Effort at Baseline — baseli…; Handgrip Strength of Dominant Hand as Measured by Handgrip Dynamometry at 100% Effort at Baseline — baseline; Handgrip Strength of Non-dominant Hand as Measured by Handgrip Dynamometry at 100% Effort at Baseline — baseline; Handgrip Fatigue of Dominant Hand as Measured by Handgrip Dynamometry at Baseline — baseline; Handgrip Fatigue of Non-dominant Hand as Measured by Handgrip Dynamometry at Baseline — baseline; Handgrip Strength of Dominant Hand as Measured by Handgrip Dynamometry at 50% Perceived Effort After All Doses of Study…; Handgrip Strength of Non-dominant Hand as Measured by Handgrip Dynamometry at 50% Perceived Effort After All Doses of S…; Handgrip Strength of Dominant Hand as Measured by Handgrip Dynamometry at 100% Perceived Effort After All Doses of Stud…; Handgrip Strength of Non-dominant Hand as Measured by Handgrip Dynamometry at 100% Perceived Effort After All Doses of…; Handgrip Fatigue of Dominant Hand as Measured by Handgrip Dynamometry After All Doses of Study Intervention — Post dose…; Handgrip Fatigue of Non-dominant Hand as Measured by Handgrip Dynamometry After All Doses of Study Intervention — Post…; Personal Perceptual Fatigue Measured by Multidimensional Fatigue Symptom Inventory - Subscale General Fatigue at Baseli…
Reported result
No reusable finding-level result is available in this record.

Main limitationThis is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.

Safety and approvalEligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians. Trial registration is not regulatory approval and does not establish that an intervention is available.

Source supportStructured registry protocol metadata; no finding-level conclusion is generated.

Trial stage · Phase 1, Phase 2A trial phase describes development stage; it does not establish a positive result.
Phase 1Phase 2Phase 3Phase 4

Registration and recruitment status do not establish safety, efficacy, or regulatory approval.

Why this record appears here · 80% topic match

The title, summary, or source keywords matched one or more topics followed by immortal.life. A higher percentage means a stronger topic match; it does not rate safety, effectiveness, or study quality.

  • Oxidative stress · 80%Title contains controlled term: oxidative stress. Title supplies longevity context: elderly. Study type is explicitly identified as INTERVENTIONAL.

Automated source check 100% · update recency 50%. These figures help sort records; they are not medical ratings.