Clinical trial registry record

Phase II Study of Subretinal JWK001 for Neovascular Age-Related Macular Degeneration

A registered PHASE2 study indexed because it matched monitored longevity research terms. Registry status: Recruiting. Registration does not establish safety or effectiveness.

Plain-language guide

Five questions to ask about this record

What this is
A clinical study registration, not a result or recommendation.
Why it may matter
The registry currently reports Recruiting.
Evidence
Registered phase 2 study.
Main limitation
Registration does not prove that the intervention works, is safe, or is available to you.
What changed
Registry metadata was last updated August 20, 2026.
Where to verify
Open the primary registry below for eligibility, locations, contacts, and current status.
Registry ID
NCT07776522
Last registry update
August 20, 2026
Status
Recruiting
Phase
Phase 2
Sponsor
West China Hospital
Enrollment
50
Countries
China
Match confidence
100%
Source feed
ClinicalTrials.gov
Automated source synopsis

A registered PHASE2 study indexed because it matched monitored longevity research terms. Registry status: Recruiting. Registration does not establish safety or effectiveness.

Evidence snapshot

What the source actually supports

Evidence stage
Phase 2
Study design
RANDOMIZED · PARALLEL · TREATMENT · NONE
Evidence population
Human clinical study registration
Participants
50
Population
ALL · 50 Years to 85 Years
Duration
2026-08-31 to 2032-01-14
Intervention
JWK001; Aflibercept (2.0 mg)
Comparator
Aflibercept Active Comparator Group
Outcomes measured
Change from baseline in best-corrected visual acuity (BCVA) — Week 34; Change from baseline in BCVA — Week 50 and Year 5; Change from baseline in central retinal thickness (CRT) — Week 34, Week 50 and Year 5; Change from baseline in the area of Macular Neovascularization (MNV) — Week 34 and Week 50; Change from baseline in leakage area — Week 34 and Week 50; Annualized mean number of rescue treatments — Week 34, Week 50 and Year 5; Change from baseline in the 25-item National Eye Institute Visual Function Questionnaire (NEI-VFQ-25) score — Week 34 a…; Frequencies and severities of all safety events — Week 34 and Year 5
Reported result
No reusable finding-level result is available in this record.

Main limitationThis is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.

Safety and approvalEligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians. Trial registration is not regulatory approval and does not establish that an intervention is available.

Source supportStructured registry protocol metadata; no finding-level conclusion is generated.

Trial stage · Phase 2A trial phase describes development stage; it does not establish a positive result.
Phase 1Phase 2Phase 3Phase 4

Registration and recruitment status do not establish safety, efficacy, or regulatory approval.

Why this record appears here · 100% topic match

The title, summary, or source keywords matched one or more topics followed by immortal.life. A higher percentage means a stronger topic match; it does not rate safety, effectiveness, or study quality.

  • Vision ageing · 100%Title contains controlled term: age-related macular degeneration. Abstract contains controlled term: age-related macular degeneration. Source terminology contains: age-related macular degeneration. Title supplies longevity context: age-related. Study type is explicitly identified as INTERVENTIONAL.

Automated source check 100% · update recency 100%. These figures help sort records; they are not medical ratings.