Clinical trial registry record

A Real-World Study to Gain Clinical Insights Into Faricimab (FaReal Study)

A registered study indexed because it matched monitored longevity research terms. Registry status: Active Not Recruiting. Registration does not establish safety or effectiveness.

Plain-language guide

Five questions to ask about this record

What this is
A clinical study registration, not a result or recommendation.
Why it may matter
The registry currently reports Active Not Recruiting.
Evidence
Registered phase not reported study.
Main limitation
Registration does not prove that the intervention works, is safe, or is available to you.
What changed
Registry metadata was last updated July 7, 2026.
Where to verify
Open the primary registry below for eligibility, locations, contacts, and current status.
Registry ID
NCT06680817
Last registry update
July 7, 2026
Status
Active Not Recruiting
Phase
Phase not reported
Sponsor
Hoffmann-La Roche
Enrollment
850
Countries
Austria, Bulgaria, Czechia, Finland, Greece, Hungary, Ireland, Israel, Latvia, Netherlands, Poland, Portugal, Romania, Slovakia, Slovenia
Match confidence
100%
Source feed
ClinicalTrials.gov
Automated source synopsis

A registered study indexed because it matched monitored longevity research terms. Registry status: Active Not Recruiting. Registration does not establish safety or effectiveness.

Evidence snapshot

What the source actually supports

Evidence stage
Phase not reported
Study design
OBSERVATIONAL
Evidence population
Human clinical study registration
Participants
850
Population
ALL · 18 Years
Duration
2025-02-05 to 2028-06-30
Intervention
Faricimab
Comparator
Not reported
Outcomes measured
Change in Visual Acuity from Index Date to 12 Months — Index Date and 12 months; Change in Visual Acuity from Index Date to 3, 6, and 24 Months — Index Date and 3, 6, and 24 months; Change in Central Subfield Thickness (CST) from Index Date to 3, 6, 12, and 24 Months — Index Date and 3, 6, 12, and 24…; Percentage of Eyes on Each Treatment Regimen (Fixed, Treat-and-Extend, As Needed, or Other) Over Time — Index Date and…; Number of Faricimab Intravitreal Injections per Eye per Year — 12 and 24 months; Number of Faricimab Intravitreal Injections in the Loading Phase for Participants who are anti-VEGF Treatment Naive or…; Total Number of Visits and Number of Visits With or Without Treatment Over Time — 3, 6, 12, and 24 months; Cumulative Time Spent in Each Treatment Regimen (Fixed, Treat-and-Extend, As Needed, or Other) — From Index Date to 24…; Percentage of Eyes With Treatment Switch from Faricimab by Reason for Switch in Participants who are anti-VEGF Treatmen…; Percentage of Eyes Obtaining Treatment Intervals of Once Every 8, 12, or 16 Weeks or Other Intervals in Participants wh…; Change in Visual Acuity from Index Date Over Time, According to Treatment Regimen (Fixed, Treat-and-Extend, As Needed,…; Change in Visual Acuity from Index Date Over Time, According to Number of Intravitreal Treatments — Index Date and 3, 6…; Change in Visual Acuity from Index Date Over Time, According to Total Number of Visits — Index Date and 3, 6, 12, and 2…; Change in Visual Acuity from Index Date Over Time, According to Treatment Intervals — Index Date and 3, 6, 12, and 24 m…; Change in Visual Acuity from Index Date Over Time, According to Type of anti-VEGF Pre-Treatment and Number of Previous…; Change in Visual Acuity from Index Date Over Time, According to Length of Diagnosis of Disease at Index Date — Index Da…; Number of Participants with at Least One Ocular Adverse Event — Approximately 2 years; Number of Participants with at Least One Non-Ocular Adverse Event — Approximately 2 years
Reported result
No reusable finding-level result is available in this record.

Main limitationThis is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.

Safety and approvalEligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians. Trial registration is not regulatory approval and does not establish that an intervention is available.

Source supportStructured registry protocol metadata; no finding-level conclusion is generated.

Trial stage · Phase not reportedA trial phase describes development stage; it does not establish a positive result.
Phase 1Phase 2Phase 3Phase 4

Registration and recruitment status do not establish safety, efficacy, or regulatory approval.

Why this record appears here · 100% topic match

The title, summary, or source keywords matched one or more topics followed by immortal.life. A higher percentage means a stronger topic match; it does not rate safety, effectiveness, or study quality.

  • Vision ageing · 100%Abstract contains controlled term: age-related macular degeneration. Source terminology contains: age-related macular degeneration. Abstract supplies longevity context: age-related. Study type is explicitly identified as OBSERVATIONAL.

Automated source check 100% · update recency 100%. These figures help sort records; they are not medical ratings.