Clinical trial registry record

To Evaluate the Safety, Pharmacokinetics, and Efficacy of GB10 Intravitreal Injection in Patients With Neovascular Age-related Macular Degeneration (nAMD)

A registered PHASE1 study indexed because it matched monitored longevity research terms. Registry status: Not Yet Recruiting. Registration does not establish safety or effectiveness.

Plain-language guide

Five questions to ask about this record

What this is
A clinical study registration, not a result or recommendation.
Why it may matter
The registry currently reports Not Yet Recruiting.
Evidence
Registered phase 1 study.
Main limitation
Registration does not prove that the intervention works, is safe, or is available to you.
What changed
Registry metadata was last updated February 12, 2026.
Where to verify
Open the primary registry below for eligibility, locations, contacts, and current status.
Registry ID
NCT07406438
Last registry update
February 12, 2026
Status
Not Yet Recruiting
Phase
Phase 1
Sponsor
Shenzhen Kexing Pharmaceutical Co., Ltd.
Enrollment
48
Countries
China
Match confidence
100%
Source feed
ClinicalTrials.gov
Automated source synopsis

A registered PHASE1 study indexed because it matched monitored longevity research terms. Registry status: Not Yet Recruiting. Registration does not establish safety or effectiveness.

Evidence snapshot

What the source actually supports

Evidence stage
Phase 1
Study design
NON RANDOMIZED · SEQUENTIAL · TREATMENT · NONE
Evidence population
Human clinical study registration
Participants
48
Population
ALL · 50 Years to 80 Years
Duration
2026-02-12 to 2027-06-30
Intervention
GB10
Comparator
Not reported
Outcomes measured
The incidence and severity of ocular adverse events — From enrollment to the end of treatment at 12 weeks; The incidence and severity of non-ocular adverse events — From enrollment to the end of treatment at 12 weeks; (SAD) The change in best corrected visual acuity (BCVA) from baseline after 4 weeks of treatment — From enrollment to t…; (MAD) The change in best corrected visual acuity (BCVA) from baseline after 12 weeks of treatment — From enrollment to…; (SAD) Change in central retinal subfield thickness (CST) from baseline at 4 weeks of treatment — From enrollment to the…; (MAD) Change in central retinal subfield thickness (CST) from baseline at 12 weeks of treatment — From enrollment to th…; Time of receiving rescue therapy for nAMD activity — From enrollment to the end of treatment at 12 weeks; Positive rate of anti-drug antibody and neutralizing antibody of GB10 — From enrollment to the end of treatment at 12 w…; Area under the drug-time curve from 0 to time t of GB10 — From enrollment to the end of treatment at 12 weeks; Area under the curve at the time of 0-infinity of GB10 — From enrollment to the end of treatment at 12 weeks; Peak concentration of GB10 — From enrollment to the end of treatment at 12 weeks; Peak time of GB10 — From enrollment to the end of treatment at 12 weeks; Clearance rate of GB10 — From enrollment to the end of treatment at 12 weeks; Half-life of GB10 — From enrollment to the end of treatment at 12 weeks; VEGF concentration — From enrollment to the end of treatment at 12 weeks; Ang2 concentration — From enrollment to the end of treatment at 12 weeks
Reported result
No reusable finding-level result is available in this record.

Main limitationThis is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.

Safety and approvalEligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians. Trial registration is not regulatory approval and does not establish that an intervention is available.

Source supportStructured registry protocol metadata; no finding-level conclusion is generated.

Trial stage · Phase 1A trial phase describes development stage; it does not establish a positive result.
Phase 1Phase 2Phase 3Phase 4

Registration and recruitment status do not establish safety, efficacy, or regulatory approval.

Why this record appears here · 100% topic match

The title, summary, or source keywords matched one or more topics followed by immortal.life. A higher percentage means a stronger topic match; it does not rate safety, effectiveness, or study quality.

  • Vision ageing · 100%Title contains controlled term: age-related macular degeneration. Abstract contains controlled term: age-related macular degeneration. Source terminology contains: age-related macular degeneration. Title supplies longevity context: age-related. Study type is explicitly identified as INTERVENTIONAL.

Automated source check 100% · update recency 85%. These figures help sort records; they are not medical ratings.