Clinical trial registry record

Pharmacogenomics of antiVEGF in Patients With Age-Associated Macular Degeneration (AMD)

A registered PHASE3 study indexed because it matched monitored longevity research terms. Registry status: Recruiting. Registration does not establish safety or effectiveness.

Plain-language guide

Five questions to ask about this record

What this is
A clinical study registration, not a result or recommendation.
Why it may matter
The registry currently reports Recruiting.
Evidence
Registered phase 3 study.
Main limitation
Registration does not prove that the intervention works, is safe, or is available to you.
What changed
Registry metadata was last updated November 20, 2025.
Where to verify
Open the primary registry below for eligibility, locations, contacts, and current status.
Registry ID
NCT06952452
Last registry update
November 20, 2025
Status
Recruiting
Phase
Phase 3
Sponsor
Parc de Salut Mar
Enrollment
630
Countries
Spain
Match confidence
100%
Source feed
ClinicalTrials.gov
Automated source synopsis

A registered PHASE3 study indexed because it matched monitored longevity research terms. Registry status: Recruiting. Registration does not establish safety or effectiveness.

Evidence snapshot

What the source actually supports

Evidence stage
Phase 3
Study design
RANDOMIZED · PARALLEL · TREATMENT · QUADRUPLE
Evidence population
Human clinical study registration
Participants
630
Population
ALL · 50 Years
Duration
2022-11-18 to 2026-07-01
Intervention
Bevacizumab; Ranibizumab Ophthalmic
Comparator
Ranibizumab, RBZ (group B)
Outcomes measured
Frequency of Genetic Polymorphism in VEGFA Associated With Anti-VEGF Treatment Response in AMD Patients — From baseline…; Change in Visual Acuity Over Time in Patients With AMD Receiving Anti-VEGF Therapy — Baseline, 6 months, 12 months, 24…; Change in Retinal Fluid and Foveal Thickness Over Time as Measured by OCT in Patients With AMD Treated With Anti-VEGF T…; Distribution of Sex Among Patients With AMD Receiving Anti-VEGF Therapy — At baseline; Distribution of Age at Diagnosis in Patients With AMD Receiving Anti-VEGF Therapy — At baseline; Proportion of Smokers Among Patients With AMD Receiving Anti-VEGF Therapy — At baseline; Weight of Patients With AMD Receiving Anti-VEGF Therapy — At baseline; Height of Patients With AMD Receiving Anti-VEGF Therapy — At baseline; Prevalence of Obesity in Patients With AMD Receiving Anti-VEGF Therapy — At baseline; Prevalence of Hypertension in Patients With AMD Receiving Anti-VEGF Therapy — At baseline; Number of Participants With Ocular and Systemic Adverse Events Associated With Intravitreal Anti-VEGF Therapy — From in…; Total Direct Healthcare Cost per Patient for Anti-VEGF Therapy Over One Year From the Health System Perspective — From…
Reported result
No reusable finding-level result is available in this record.

Main limitationThis is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.

Safety and approvalEligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians. Trial registration is not regulatory approval and does not establish that an intervention is available.

Source supportStructured registry protocol metadata; no finding-level conclusion is generated.

Trial stage · Phase 3A trial phase describes development stage; it does not establish a positive result.
Phase 1Phase 2Phase 3Phase 4

Registration and recruitment status do not establish safety, efficacy, or regulatory approval.

Why this record appears here · 100% topic match

The title, summary, or source keywords matched one or more topics followed by immortal.life. A higher percentage means a stronger topic match; it does not rate safety, effectiveness, or study quality.

  • Vision ageing · 100%Abstract contains controlled term: age-related macular degeneration. Source terminology contains: age-related macular degeneration. Abstract supplies longevity context: age-related. Study type is explicitly identified as INTERVENTIONAL.

Automated source check 100% · update recency 85%. These figures help sort records; they are not medical ratings.