Clinical trial registry record

A Dose Escalation Study of IBI302 in Patients With Wet Age-related Macular Degeneration

A registered PHASE1 study indexed because it matched monitored longevity research terms. Registry status: Completed. Registration does not establish safety or effectiveness.

Plain-language guide

Five questions to ask about this record

What this is
A clinical study registration, not a result or recommendation.
Why it may matter
The registry currently reports Completed.
Evidence
Registered phase 1 study.
Main limitation
Registration does not prove that the intervention works, is safe, or is available to you.
What changed
Registry metadata was last updated April 17, 2025.
Where to verify
Open the primary registry below for eligibility, locations, contacts, and current status.
Registry ID
NCT03814291
Last registry update
April 17, 2025
Status
Completed
Phase
Phase 1
Sponsor
Innovent Biologics (Suzhou) Co. Ltd.
Enrollment
31
Countries
China
Match confidence
100%
Source feed
ClinicalTrials.gov
Automated source synopsis

A registered PHASE1 study indexed because it matched monitored longevity research terms. Registry status: Completed. Registration does not establish safety or effectiveness.

Evidence snapshot

What the source actually supports

Evidence stage
Phase 1
Study design
NON RANDOMIZED · SINGLE GROUP · TREATMENT · NONE
Evidence population
Human clinical study registration
Participants
31
Population
ALL · 50 Years
Duration
2019-04-15 to 2020-04-10
Intervention
IBI302
Comparator
Not reported
Outcomes measured
Safety evaluation indicators — Baseline to Day43; Efficacy evaluation indicators — Baseline to Day43; Immunogenicity evaluation indicators — Baseline to Day43; The area under the drug-time curve from 0 to time t (AUC0-t) — Baseline to Day43; The area under the curve at the time of 0-infinity (AUC0-∞) — Baseline to Day43; The peak concentration (Cmax) — Baseline to Day43; The peak time (Tmax) — Baseline to Day43; Clearance rate (CL) — Baseline to Day43; Half-life (t1/2) — Baseline to Day43; Free and total VEGF concentration — Baseline to Day43
Reported result
No reusable finding-level result is available in this record.

Main limitationThis is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.

Safety and approvalEligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians. Trial registration is not regulatory approval and does not establish that an intervention is available.

Source supportStructured registry protocol metadata; no finding-level conclusion is generated.

Trial stage · Phase 1A trial phase describes development stage; it does not establish a positive result.
Phase 1Phase 2Phase 3Phase 4

Registration and recruitment status do not establish safety, efficacy, or regulatory approval.

Why this record appears here · 100% topic match

The title, summary, or source keywords matched one or more topics followed by immortal.life. A higher percentage means a stronger topic match; it does not rate safety, effectiveness, or study quality.

  • Vision ageing · 100%Title contains controlled term: age-related macular degeneration. Source terminology contains: age-related macular degeneration. Title supplies longevity context: age-related. Study type is explicitly identified as INTERVENTIONAL.

Automated source check 100% · update recency 65%. These figures help sort records; they are not medical ratings.