Clinical trial registry record

Regulatory Post-Marketing Surveillance Study for Brolucizumab

A registered study indexed because it matched monitored longevity research terms. Registry status: Recruiting. Registration does not establish safety or effectiveness.

Plain-language guide

Five questions to ask about this record

What this is
A clinical study registration, not a result or recommendation.
Why it may matter
The registry currently reports Recruiting.
Evidence
Registered phase not reported study.
Main limitation
Registration does not prove that the intervention works, is safe, or is available to you.
What changed
Registry metadata was last updated January 14, 2025.
Where to verify
Open the primary registry below for eligibility, locations, contacts, and current status.
Registry ID
NCT04985487
Last registry update
January 14, 2025
Status
Recruiting
Phase
Phase not reported
Sponsor
Novartis Pharmaceuticals
Enrollment
3000
Countries
South Korea
Match confidence
60%
Source feed
ClinicalTrials.gov
Automated source synopsis

A registered study indexed because it matched monitored longevity research terms. Registry status: Recruiting. Registration does not establish safety or effectiveness.

Evidence snapshot

What the source actually supports

Evidence stage
Phase not reported
Study design
OBSERVATIONAL
Evidence population
Human clinical study registration
Participants
3000
Population
ALL · 18 Years to 100 Years
Duration
2021-08-18 to 2026-06-14
Intervention
brolucizumab
Comparator
Not reported
Outcomes measured
Incidence of adverse events at 12 weeks — 12 weeks; Incidence of adverse events at 24 weeks and optionally at 36 weeks — Up to 36 weeks; Proportion of patients gaining or losing more than 15 letters on the ETDRS chart — Week 12, week 24, optionally week 36; Mean change of Central Subfield Thickness (CST) from baseline — Baseline, week 12, week 24, optionally week 36; Mean change of Best Corrected Visual Acuity (BCVA) from baseline — Baseline, week 12, week 24, optionally week 36; Mean Best Corrected Visual Acuity (BCVA) — Baseline, week 12, week 24, optionally week 36; Mean Central Subfield Thickness (CST) — Baseline, Week 12, week 24, optionally week 36; Number of injections — Up to 36 weeks; Percentage of patients completing the loading phase — 4 months; Percentage of patients who maintained with 12 weeks interval — Up to 36 weeks; Proportion of patients with retinal fluid — Week 12, week 24, optionally week 36; Prior anti-VEGF treatment history - number of prior injections — Baseline; Prior anti-VEGF treatment history - agent of prior injections — Baseline; Predictive factors of treatment outcomes (persistent disease activity) — Week 24; Treatment naïve/non-naïve — Baseline; Treatment interval — Up to week 36; Concomitant treatments — Baseline; Number of participants with post injection empirical treatment — Week 12, week 24, optionally week 36
Reported result
No reusable finding-level result is available in this record.

Main limitationThis is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.

Safety and approvalEligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians. Trial registration is not regulatory approval and does not establish that an intervention is available.

Source supportStructured registry protocol metadata; no finding-level conclusion is generated.

Trial stage · Phase not reportedA trial phase describes development stage; it does not establish a positive result.
Phase 1Phase 2Phase 3Phase 4

Registration and recruitment status do not establish safety, efficacy, or regulatory approval.

Why this record appears here · 60% topic match

The title, summary, or source keywords matched one or more topics followed by immortal.life. A higher percentage means a stronger topic match; it does not rate safety, effectiveness, or study quality.

  • Vision ageing · 60%Source terminology contains: age-related macular degeneration. Source terminology supplies longevity context: age-related. Study type is explicitly identified as OBSERVATIONAL.

Automated source check 100% · update recency 65%. These figures help sort records; they are not medical ratings.