Clinical trial registry record

A Study to Evaluate Real-world Brolucizumab Effectiveness and Safety in Japanese Patients With Neovascular Age-related Macular Degeneration (nAMD)

A registered study indexed because it matched monitored longevity research terms. Registry status: Completed. Registration does not establish safety or effectiveness.

Plain-language guide

Five questions to ask about this record

What this is
A clinical study registration, not a result or recommendation.
Why it may matter
The registry currently reports Completed.
Evidence
Registered phase not reported study.
Main limitation
Registration does not prove that the intervention works, is safe, or is available to you.
What changed
Registry metadata was last updated November 21, 2024.
Where to verify
Open the primary registry below for eligibility, locations, contacts, and current status.
Registry ID
NCT06699914
Last registry update
November 21, 2024
Status
Completed
Phase
Phase not reported
Sponsor
Novartis Pharmaceuticals
Enrollment
438
Countries
United States
Match confidence
100%
Source feed
ClinicalTrials.gov
Automated source synopsis

A registered study indexed because it matched monitored longevity research terms. Registry status: Completed. Registration does not establish safety or effectiveness.

Evidence snapshot

What the source actually supports

Evidence stage
Phase not reported
Study design
OBSERVATIONAL
Evidence population
Human clinical study registration
Participants
438
Population
ALL · 50 Years
Duration
2022-09-06 to 2023-12-01
Intervention
Comparator
Not reported
Outcomes measured
Number of Patients With Absence of Intra-retinal Fluid (IRF) and Absence of Subretinal Fluid (SRF) at Month 12 — Month…; Number of Patients With Absence of IRF and Absence of SRF at Month 3, 6, 9, and 18 — Month 3, 6, 9, and 18; Demographic: Age — Baseline; Demographic: Number of Patients per Age Category — Baseline; Demographic: Gender — Baseline; Number of Patients per Clinical Characteristic — Baseline; Clinical Characteristic: Time Between Diagnosis and First Brolucizumab Injection — Baseline; Clinical Characteristic: Time Between Diagnosis and First Treatment — Baseline; Clinical Characteristic: Central Subfield Thickness (CSFT) — Baseline; Clinical Characteristic: Visual Acuity (VA) — Baseline; Clinical Characteristic: VA in Each Subtype — Baseline; Number of Patients by Type of Previous Anti-vascular Endothelial Growth Factor (Anti-VEGF) Treatment — Up to 12 months…; Last Injection Interval of Anti-VEGF Treatment Before Switching — Up to 12 months pre-baseline; Number of Injections in the Last 6 Months Before Switching to Brolucizumab — Up to 6 months pre-baseline; Number of Injections in the Last 6 Months After Switching to Brolucizumab — Up to 6 months post-baseline; Number of Injections in the Last 12 Months Before Switching to Brolucizumab — Up to 12 months pre-baseline; Number of Injections in the Last 12 Months After Switching to Brolucizumab — Up to 12 months post-baseline; Number of Patients With Absence of Subretinal Fluid (SRF) — Month 3, 6, 9, 12 and 18; Number of Patients with Absence of Intra-retinal Fluid (IRF) — Month 3, 6, 9, 12, and 18; Number of Patients with Absence of Sub-retinal Pigment Epithelium (sub-RPE) Fluid — Month 3, 6, 9, 12, and 18
Reported result
No reusable finding-level result is available in this record.

Main limitationThis is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.

Safety and approvalEligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians. Trial registration is not regulatory approval and does not establish that an intervention is available.

Source supportStructured registry protocol metadata; no finding-level conclusion is generated.

Trial stage · Phase not reportedA trial phase describes development stage; it does not establish a positive result.
Phase 1Phase 2Phase 3Phase 4

Registration and recruitment status do not establish safety, efficacy, or regulatory approval.

Why this record appears here · 100% topic match

The title, summary, or source keywords matched one or more topics followed by immortal.life. A higher percentage means a stronger topic match; it does not rate safety, effectiveness, or study quality.

  • Vision ageing · 100%Title contains controlled term: age-related macular degeneration. Source terminology contains: age-related macular degeneration. Title supplies longevity context: age-related. Study type is explicitly identified as OBSERVATIONAL.

Automated source check 100% · update recency 65%. These figures help sort records; they are not medical ratings.