Clinical trial registry record

Brolucizumab Treatment Experience Study of Patients With nAMD in UK Routine Clinical Practice

A registered study indexed because it matched monitored longevity research terms. Registry status: Terminated. Registration does not establish safety or effectiveness.

Plain-language guide

Five questions to ask about this record

What this is
A clinical study registration, not a result or recommendation.
Why it may matter
The registry currently reports Terminated.
Evidence
Registered phase not reported study.
Main limitation
Registration does not prove that the intervention works, is safe, or is available to you.
What changed
Registry metadata was last updated October 29, 2024.
Where to verify
Open the primary registry below for eligibility, locations, contacts, and current status.
Registry ID
NCT05112835
Last registry update
October 29, 2024
Status
Terminated
Phase
Phase not reported
Sponsor
Novartis Pharmaceuticals
Enrollment
302
Countries
United Kingdom
Match confidence
60%
Source feed
ClinicalTrials.gov
Automated source synopsis

A registered study indexed because it matched monitored longevity research terms. Registry status: Terminated. Registration does not establish safety or effectiveness.

Evidence snapshot

What the source actually supports

Evidence stage
Phase not reported
Study design
OBSERVATIONAL
Evidence population
Human clinical study registration
Participants
302
Population
ALL · 50 Years
Duration
2021-11-19 to 2022-09-08
Intervention
brolucizumab
Comparator
Not reported
Outcomes measured
Percentage (%) of patients with absence of retinal fluid — Month 12; Percentage (%) of patients with absence of SRF — Month 3, month 6, month 12, month 24, month 36, month 48 and month 60; Percentage (%) of patients with absence of IRF — Month 3, month 6, month 12, month 24, month 36, month 48 and month 60; Percentage (%) of patients with absence of sub-RPE fluid — Month 3, month 6, month 12, month 24, month 36, month 48 and…; Percentage (%) of patients with absence of PED — Month 3, month 6, month 12, month 24, month 36, month 48 and month 60; Percentage (%) of patients with absence of retinal fluid — Month 3, month 6, month 12, month 24, month 36, month 48 and…; CRT change from baseline — Baseline, month 3, month 6, month 12, month 24, month 36, month 48 and month 60; CST change from baseline — Baseline, month 3, month 6, month 12, month 24, month 36, month 48 and month 60; BCVA change from baseline — Baseline, month 3, month 6, month 12, month 24, month 36, month 48 and month 60; Percentage (%) of patients with BCVA ≥70 ETDRS letters — Month 3, month 6, month 12, month 24, month 36, month 48 and m…; Total number of injections received — Up to 60 months; Duration of injection intervals per patient — Up to 60 months; Percentage (%) of patients with ≥3 brolucizumab injections — Month 3; Percentage (%) of patients who switch from brolucizumab to another anti-VEGF — Month 12, month 24, month 36, month 48 a…; Percentage (%) of patients that discontinue Brolucizumab therapy — Up to 60 months; Percentage (%) of patients with IOI including RV and RVO — Up to 60 months; Percentage (%) of patients with disease control — Month 12 and month 24; Change in macular volume of IRF/SRF by central reading center — Baseline at Month 12
Reported result
No reusable finding-level result is available in this record.

Main limitationThis is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.

Safety and approvalEligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians. Trial registration is not regulatory approval and does not establish that an intervention is available.

Source supportStructured registry protocol metadata; no finding-level conclusion is generated.

Trial stage · Phase not reportedA trial phase describes development stage; it does not establish a positive result.
Phase 1Phase 2Phase 3Phase 4

Registration and recruitment status do not establish safety, efficacy, or regulatory approval.

Why this record appears here · 60% topic match

The title, summary, or source keywords matched one or more topics followed by immortal.life. A higher percentage means a stronger topic match; it does not rate safety, effectiveness, or study quality.

  • Vision ageing · 60%Source terminology contains: age-related macular degeneration. Source terminology supplies longevity context: age-related. Study type is explicitly identified as OBSERVATIONAL.

Automated source check 100% · update recency 65%. These figures help sort records; they are not medical ratings.