Clinical trial registry record

A Study to Test How Well Different Doses of BI 754132 Are Tolerated in Patients With an Advanced Form of Age-related Macular Degeneration Called Geographic Atrophy

A registered PHASE1 study indexed because it matched monitored longevity research terms. Registry status: Terminated. Registration does not establish safety or effectiveness.

Plain-language guide

Five questions to ask about this record

What this is
A clinical study registration, not a result or recommendation.
Why it may matter
The registry currently reports Terminated.
Evidence
Registered phase 1 study.
Main limitation
Registration does not prove that the intervention works, is safe, or is available to you.
What changed
Registry metadata was last updated September 15, 2023.
Where to verify
Open the primary registry below for eligibility, locations, contacts, and current status.
Registry ID
NCT04002310
Last registry update
September 15, 2023
Status
Terminated
Phase
Phase 1
Sponsor
Boehringer Ingelheim
Enrollment
18
Countries
United States, United Kingdom
Match confidence
100%
Source feed
ClinicalTrials.gov
Automated source synopsis

A registered PHASE1 study indexed because it matched monitored longevity research terms. Registry status: Terminated. Registration does not establish safety or effectiveness.

Evidence snapshot

What the source actually supports

Evidence stage
Phase 1
Study design
NON RANDOMIZED · SEQUENTIAL · TREATMENT · NONE
Evidence population
Human clinical study registration
Participants
18
Population
ALL · 50 Years
Duration
2019-07-26 to 2022-08-09
Intervention
BI 754132
Comparator
Not reported
Outcomes measured
SRD Part: Number of Patients With Ocular (in the Study Eye) or Systemic Dose Limiting Events (DLEs) — From drug adminis…; MD Part: Number of Patients With Drug Related Adverse Events (AEs) — From drug administration until end of trial, up to…; SRD Part: Number of Patients With Drug-related Adverse Events (AEs) — From drug administration until end of trial, up t…; SRD Part: Number of Patients With Any Ocular Adverse Events (AEs) in the Study Eye — From drug administration until end…; SRD Part: Maximum Serum Concentration of BI 754132 After a Single Intravitreal Dose (Cmax) — At Day 1, 4, 8, 15, 29, 56…; SRD Part: Area Under the Concentration-time Curve of BI 754132 in Serum Over the Time Interval From 0 Extrapolated to I…; SRD Part: Time From Dosing to Maximum Serum Concentration of BI 754132 (Tmax) — At Day 1, 4, 8, 15, 29, 56, 84 and Day…; MD Part: Trough Levels of BI 754132 Before Second Administration (Cmin,1) — Up to 29 days.; MD Part: Trough Levels of BI 754132 Before Third Administration (Cmin,2) — Up to 57 days.; MD Part: Plasma Concentration of BI 754132 4, 8 and 14 Weeks After the Third Administration — At Day 85, 113 and Day 15…
Reported result
No reusable finding-level result is available in this record.

Main limitationThis is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.

Safety and approvalEligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians. Trial registration is not regulatory approval and does not establish that an intervention is available.

Source supportStructured registry protocol metadata; no finding-level conclusion is generated.

Trial stage · Phase 1A trial phase describes development stage; it does not establish a positive result.
Phase 1Phase 2Phase 3Phase 4

Registration and recruitment status do not establish safety, efficacy, or regulatory approval.

Why this record appears here · 100% topic match

The title, summary, or source keywords matched one or more topics followed by immortal.life. A higher percentage means a stronger topic match; it does not rate safety, effectiveness, or study quality.

  • Vision ageing · 100%Title contains controlled term: age-related macular degeneration. Abstract contains controlled term: age-related macular degeneration. Title supplies longevity context: age-related. Study type is explicitly identified as INTERVENTIONAL.

Automated source check 100% · update recency 50%. These figures help sort records; they are not medical ratings.