Clinical trial registry record

Effect on Pain and Inflammation With DEXTENZA Treatment in Patients Undergoing Intravitreal Anti-VEGF Injections

A registered PHASE4 study indexed because it matched monitored longevity research terms. Registry status: Terminated. Registration does not establish safety or effectiveness.

Plain-language guide

Five questions to ask about this record

What this is
A clinical study registration, not a result or recommendation.
Why it may matter
The registry currently reports Terminated.
Evidence
Registered phase 4 study.
Main limitation
Registration does not prove that the intervention works, is safe, or is available to you.
What changed
Registry metadata was last updated February 22, 2023.
Where to verify
Open the primary registry below for eligibility, locations, contacts, and current status.
Registry ID
NCT04563299
Last registry update
February 22, 2023
Status
Terminated
Phase
Phase 4
Sponsor
Retina Vitreous Associates of Florida
Enrollment
10
Countries
United States
Match confidence
60%
Source feed
ClinicalTrials.gov
Automated source synopsis

A registered PHASE4 study indexed because it matched monitored longevity research terms. Registry status: Terminated. Registration does not establish safety or effectiveness.

Evidence snapshot

What the source actually supports

Evidence stage
Phase 4
Study design
RANDOMIZED · PARALLEL · TREATMENT · DOUBLE
Evidence population
Human clinical study registration
Participants
10
Population
ALL · 18 Years
Duration
2020-12-09 to 2023-02-14
Intervention
Dextenza 0.4Mg Ophthalmic Insert; Prednisolone Acetate
Comparator
Topical Corticosteroids
Outcomes measured
Mean Change in Pain Scores — As assessed at Baseline Visit, 6 hours (+/- 2 hours), 24 hours (+/- 3 hours), and at 3-6 d…; Overall Proportion of Eyes with Absence of AC Cell/Flare (Score of 0) — Assessed 3-6 days following Injection Visit 1,…; Proportion of eyes with absence of AC cells/flare (score of 0) — Assessed at 3-6 days following Injection Visit 1, Inje…; Correlation of pain scale outcomes with absence or presence of AC cell count and flare scores — Assessed at 3-6 days af…; Mean Change in pain scores — As assessed at Baseline Visit, 6 hours (+/- 2 hours), 24 hours (+/- 3 hours), and at 3-6 d…; Patient Comfort — As assessed at Baseline Visit, 6 hours (+/- 2 hours), 24 hours (+/- 3 hours), and at 3-6 days after I…; Mean Change in Tear Break-up Time — As assessed at Baseline Visit, Injection Visit 1, Injection Visit 2, Injection Visi…; Mean Change in Snellen and Pinhole Acuity — As assessed at Baseline Visit, Injection Visit 1, Injection Visit 2, and In…; Mean change in IOP — As assessed at Baseline Visit, Injection Visit 1, Injection Visit 2, and Injection Visit 3, and th…; Patient Preference — As assessed at the Final Post-Injection Follow-up Visit (up to 24 weeks); Incidence and severity of adverse events — As assessed at Baseline, 6 hours (+/- 2 hours), 24 hours (+/- 3 hours), 3-6…
Reported result
No reusable finding-level result is available in this record.

Main limitationThis is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.

Safety and approvalEligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians. Trial registration is not regulatory approval and does not establish that an intervention is available.

Source supportStructured registry protocol metadata; no finding-level conclusion is generated.

Trial stage · Phase 4A trial phase describes development stage; it does not establish a positive result.
Phase 1Phase 2Phase 3Phase 4

Registration and recruitment status do not establish safety, efficacy, or regulatory approval.

Why this record appears here · 60% topic match

The title, summary, or source keywords matched one or more topics followed by immortal.life. A higher percentage means a stronger topic match; it does not rate safety, effectiveness, or study quality.

  • Vision ageing · 60%Source terminology contains: age-related macular degeneration. Source terminology supplies longevity context: age-related. Study type is explicitly identified as INTERVENTIONAL.

Automated source check 100% · update recency 50%. These figures help sort records; they are not medical ratings.