Clinical trial registry record

Aflibercept After Ranibizumab in Exudative Age-related Macular Degeneration

A registered PHASE3 study indexed because it matched monitored longevity research terms. Registry status: Completed. Registration does not establish safety or effectiveness.

Plain-language guide

Five questions to ask about this record

What this is
A clinical study registration, not a result or recommendation.
Why it may matter
The registry currently reports Completed.
Evidence
Registered phase 3 study.
Main limitation
Registration does not prove that the intervention works, is safe, or is available to you.
What changed
Registry metadata was last updated December 6, 2022.
Where to verify
Open the primary registry below for eligibility, locations, contacts, and current status.
Registry ID
NCT02157077
Last registry update
December 6, 2022
Status
Completed
Phase
Phase 3
Sponsor
Centre Hospitalier Intercommunal Creteil
Enrollment
90
Countries
France
Match confidence
80%
Source feed
ClinicalTrials.gov
Automated source synopsis

A registered PHASE3 study indexed because it matched monitored longevity research terms. Registry status: Completed. Registration does not establish safety or effectiveness.

Evidence snapshot

What the source actually supports

Evidence stage
Phase 3
Study design
NA · SINGLE GROUP · TREATMENT · NONE
Evidence population
Human clinical study registration
Participants
90
Population
ALL · 50 Years
Duration
2013-12-01 to 2015-12-01
Intervention
Aflibercept
Comparator
Not reported
Outcomes measured
Change from baseline in maximal height of pigment epithelium detachment (PED) at 12 weeks — Baseline and 12 weeks; Change from baseline in central retinal thickness by SD OCT at 12 weeks — Baseline and 12 weeks; Change from Baseline in visual acuity at 12 weeks — Baseline and 12 weeks; Change from Baseline in volume of pigment epithelium detachment at 12 weeks — Baseline and 12 weeks; Association with genes involved in AMD history — genetic testing will be performed when all the particpitants will be r…; Number of participants with adverse events from baseline to 32 weeks — from baseline to 32 weeks; Change from Baseline in pigment epithelium detachment height at 12 weeks — Baseline and 12 weeks; Change from baseline in central retinal thickness at 32 weeks — baseline and 32 weeks; Change from Baseline in pigment epithelium detachment height at 32 weeks — Baseline and 32 weeks; Change from Baseline in visual acuity at 32 weeks — Baseline and 32 weeks; Change from Baseline in volume of pigment epithelium detachment at 32 weeks — Baseline and 32 weeks
Reported result
No reusable finding-level result is available in this record.

Main limitationThis is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.

Safety and approvalEligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians. Trial registration is not regulatory approval and does not establish that an intervention is available.

Source supportStructured registry protocol metadata; no finding-level conclusion is generated.

Trial stage · Phase 3A trial phase describes development stage; it does not establish a positive result.
Phase 1Phase 2Phase 3Phase 4

Registration and recruitment status do not establish safety, efficacy, or regulatory approval.

Why this record appears here · 80% topic match

The title, summary, or source keywords matched one or more topics followed by immortal.life. A higher percentage means a stronger topic match; it does not rate safety, effectiveness, or study quality.

  • Vision ageing · 80%Title contains controlled term: age-related macular degeneration. Title supplies longevity context: age-related. Study type is explicitly identified as INTERVENTIONAL.

Automated source check 100% · update recency 50%. These figures help sort records; they are not medical ratings.