Clinical trial registry record

Impact of a Melatonin Supplementation on the Quality of Life in Elderly Metastatic Cancer Patients

A registered PHASE3 study indexed because it matched monitored longevity research terms. Registry status: Terminated. Registration does not establish safety or effectiveness.

Plain-language guide

Five questions to ask about this record

What this is
A clinical study registration, not a result or recommendation.
Why it may matter
The registry currently reports Terminated.
Evidence
Registered phase 3 study.
Main limitation
Registration does not prove that the intervention works, is safe, or is available to you.
What changed
Registry metadata was last updated June 13, 2022.
Where to verify
Open the primary registry below for eligibility, locations, contacts, and current status.
Registry ID
NCT02454855
Last registry update
June 13, 2022
Status
Terminated
Phase
Phase 3
Sponsor
Centre Jean Perrin
Enrollment
123
Countries
France
Match confidence
100%
Source feed
ClinicalTrials.gov
Automated source synopsis

A registered PHASE3 study indexed because it matched monitored longevity research terms. Registry status: Terminated. Registration does not establish safety or effectiveness.

Evidence snapshot

What the source actually supports

Evidence stage
Phase 3
Study design
RANDOMIZED · PARALLEL · SUPPORTIVE CARE · QUADRUPLE
Evidence population
Human clinical study registration
Participants
123
Population
ALL · 70 Years
Duration
2015-07-01 to 2022-02-01
Intervention
melatonin; placebo
Comparator
Group "Placebo"
Outcomes measured
comparison of average individual variation of overall score of QLQ-C30 of the 2 groups "Melatonin" and control (placebo…; Sub-scores of QLQ-C30 questionnaire especially dimensions "symptoms" and "functional" — 1 year; longitudinal evolution of QLQ-C30 scores — 1 year; Evolution of scores of QLQ-ELD14 — 1 year; sleep quality: Questionnaire Leeds — 1 year; Fatigue: visual analog scale (VAS) — 1 year; Pain: VAS — 1 year; Depression: Questionnaire GDS (Geriatric Depression Scale) — 1 year; Tolerance: assessed and graded according to the NCI-CTC (National Cancer Institute Common Toxicity Criteria) version 4.…; one year Overall survival rate — 1 year; one year recurrence-free survival rate — 1 year; Cognitive function: MMS (mini-mental score) or Folstein test — 1 year; Evaluation of autonomy: ADL-IADL questionnaires — 1 year; Compliance to treatment — 3 months; evaluation of the appetite with an EVA — 1 year; evaluation of Dietary intake with dietary questionnaires — 1 year; Secretion of melatonin: urinary concentration of 6-sulfatoxy-melatonin (urine night 12h), with normalization on creatin…; Circadian rhythms of activity / rest: survey using actimeters worn for 48 hours — baseline and after 3 months of treatm…
Reported result
No reusable finding-level result is available in this record.

Main limitationThis is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.

Safety and approvalEligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians. Trial registration is not regulatory approval and does not establish that an intervention is available.

Source supportStructured registry protocol metadata; no finding-level conclusion is generated.

Trial stage · Phase 3A trial phase describes development stage; it does not establish a positive result.
Phase 1Phase 2Phase 3Phase 4

Registration and recruitment status do not establish safety, efficacy, or regulatory approval.

Why this record appears here · 100% topic match

The title, summary, or source keywords matched one or more topics followed by immortal.life. A higher percentage means a stronger topic match; it does not rate safety, effectiveness, or study quality.

  • Cancer and ageing · 100%Title contains controlled topic terminology. Summary contains controlled topic terminology. Source terminology contains a controlled topic term. Title supplies ageing or longevity context.

Automated source check 100% · update recency 50%. These figures help sort records; they are not medical ratings.

cancer and aging
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