Clinical trial registry record

Safety, Efficacy of FFP From Healthy Donors to Ameliorate Frailty and Enhance Immune Function in Older Individuals

A registered PHASE1, PHASE2 study indexed because it matched monitored longevity research terms. Registry status: Enrolling By Invitation. Registration does not establish safety or effectiveness.

Plain-language guide

Five questions to ask about this record

What this is
A clinical study registration, not a result or recommendation.
Why it may matter
The registry currently reports Enrolling By Invitation.
Evidence
Registered phase 1, phase 2 study.
Main limitation
Registration does not prove that the intervention works, is safe, or is available to you.
What changed
Registry metadata was last updated May 1, 2026.
Where to verify
Open the primary registry below for eligibility, locations, contacts, and current status.
Registry ID
NCT03458429
Last registry update
May 1, 2026
Status
Enrolling By Invitation
Phase
Phase 1, Phase 2
Sponsor
Dipnarine Maharaj
Enrollment
30
Countries
United States
Match confidence
100%
Source feed
ClinicalTrials.gov
Automated source synopsis

A registered PHASE1, PHASE2 study indexed because it matched monitored longevity research terms. Registry status: Enrolling By Invitation. Registration does not establish safety or effectiveness.

Evidence snapshot

What the source actually supports

Evidence stage
Phase 1, Phase 2
Study design
NA · SINGLE GROUP · TREATMENT · NONE
Evidence population
Human clinical study registration
Participants
30
Population
ALL · 55 Years to 95 Years
Duration
2018-02-05 to 2030-12-30
Intervention
GMFFP
Comparator
Not reported
Outcomes measured
Number of participants with treatment-related adverse events as assessed by clinical symptoms, laboratory abnormalities…; Efficacy outcomes as measured by changes from baseline at 12 and 24 months assessing Immune Risk Profile (IRP) — 12 and…; Efficacy outcomes as measured by changes from baseline at 12 and 24 months assessing cognitive function (MME) — 12 and…; Efficacy outcomes as measured by changes from baseline at 12 and 24 months assessing quality of life (OPQOL-35) — 12 an…; Efficacy outcomes as measured by changes from baseline at 12 and 24 months assessing Frailty Index (FI) — 12 and 24 mon…
Reported result
No reusable finding-level result is available in this record.

Main limitationThis is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.

Safety and approvalEligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians. Trial registration is not regulatory approval and does not establish that an intervention is available.

Source supportStructured registry protocol metadata; no finding-level conclusion is generated.

Trial stage · Phase 1, Phase 2A trial phase describes development stage; it does not establish a positive result.
Phase 1Phase 2Phase 3Phase 4

Registration and recruitment status do not establish safety, efficacy, or regulatory approval.

Why this record appears here · 100% topic match

The title, summary, or source keywords matched one or more topics followed by immortal.life. A higher percentage means a stronger topic match; it does not rate safety, effectiveness, or study quality.

  • Frailty · 100%Title contains controlled term: frailty. Abstract contains controlled term: frailty, frailty index. Source terminology contains: frailty. Title supplies longevity context: frailty, frail. Study type is explicitly identified as INTERVENTIONAL.

Automated source check 100% · update recency 100%. These figures help sort records; they are not medical ratings.

frailty
Open primary sourceExport JSON