Clinical trial registry record

Evaluation of Urolithin A and Fisetin on Improving Sleep and Aging Biomarkers

A registered study indexed because it matched monitored longevity research terms. Registry status: Active Not Recruiting. Registration does not establish safety or effectiveness.

Plain-language guide

Five questions to ask about this record

What this is
A clinical study registration, not a result or recommendation.
Why it may matter
The registry currently reports Active Not Recruiting.
Evidence
Registered phase not reported study.
Main limitation
Registration does not prove that the intervention works, is safe, or is available to you.
What changed
Registry metadata was last updated August 10, 2026.
Where to verify
Open the primary registry below for eligibility, locations, contacts, and current status.
Registry ID
NCT06990256
Last registry update
August 10, 2026
Status
Active Not Recruiting
Phase
Phase not reported
Sponsor
Huazhong University of Science and Technology
Enrollment
83
Countries
China
Match confidence
100%
Source feed
ClinicalTrials.gov
Automated source synopsis

A registered study indexed because it matched monitored longevity research terms. Registry status: Active Not Recruiting. Registration does not establish safety or effectiveness.

Evidence snapshot

What the source actually supports

Evidence stage
Phase not reported
Study design
RANDOMIZED · PARALLEL · TREATMENT · QUADRUPLE
Evidence population
Human clinical study registration
Participants
83
Population
ALL · 30 Years to 75 Years
Duration
2025-09-16 to 2026-12-30
Intervention
Fisetin intervention; Placebo; Urolithin A intervention
Comparator
Placebo Control group
Outcomes measured
Subjective Sleep Quality Score — From enrollment to the end of intervention at 12 weeks; Chronotype — From enrollment to the end of intervention at 12 weeks; Polysomnography — From enrollment to the end of intervention at 12 weeks; Number of participants with abnormal blood and urine routine tests results — From enrollment to the end of intervention…; Homeostatic Model Assessment of Insulin Resistance — From enrollment to the end of intervention at 12 weeks; Frailty Assessment — From enrollment to the end of intervention at 12 weeks; Fatigue Severity Scale Score — From enrollment to the end of intervention at 12 weeks; Patient Health Questionnaire-9 Score — From enrollment to the end of intervention at 12 weeks; Generalized Anxiety Disorder Scale Score — From enrollment to the end of intervention at 12 weeks; Determination of Plasma Immunoglobulin Levels (g/L) — From enrollment to the end of intervention at 12 weeks; DNA Methylation Clock — From enrollment to the end of intervention at 12 weeks; Profile of Mood States-Short Form (Chinese Version) Score — From enrollment to the end of intervention at 12 weeks; Plasma Interleukin Levels — From enrollment to the end of intervention at 12 weeks; Gut Microbiota Diversity Analysis (Based on 16S rRNA Gene Sequencing) — From enrollment to the end of intervention at 1…; D-lactic acid level — From enrollment to the end of intervention at 12 weeks; NAD+ Level Measurement — From enrollment to the end of intervention at 12 weeks; Quality of Life Assessment — From enrollment to the end of intervention at 12 weeks; Arterial stiffness assessment — From enrollment to the end of intervention at 12 weeks; Cardiopulmonary exercise testing — From enrollment to the end of intervention at 12 weeks
Reported result
No reusable finding-level result is available in this record.

Main limitationThis is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.

Safety and approvalEligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians. Trial registration is not regulatory approval and does not establish that an intervention is available.

Source supportStructured registry protocol metadata; no finding-level conclusion is generated.

Trial stage · Phase not reportedA trial phase describes development stage; it does not establish a positive result.
Phase 1Phase 2Phase 3Phase 4

Registration and recruitment status do not establish safety, efficacy, or regulatory approval.

Why this record appears here · 100% topic match

The title, summary, or source keywords matched one or more topics followed by immortal.life. A higher percentage means a stronger topic match; it does not rate safety, effectiveness, or study quality.

  • Biological age biomarkers · 100%Title contains controlled term: aging biomarker. Abstract contains controlled term: aging biomarker. Title supplies longevity context: aging. Study type is explicitly identified as INTERVENTIONAL.
  • Sleep · 100%Title contains controlled term: sleep. Abstract contains controlled term: sleep. Source terminology contains: sleep. Title supplies longevity context: aging. Study type is explicitly identified as INTERVENTIONAL.
  • Urolithin A · 100%Title contains controlled term: urolithin a. Abstract contains controlled term: urolithin a. Source terminology contains: urolithin a. Title supplies longevity context: aging. Study type is explicitly identified as INTERVENTIONAL.

Automated source check 100% · update recency 100%. These figures help sort records; they are not medical ratings.