Clinical trial registry record

Circadian Health Regulation and Optimization for Rejuvenation Outcomes

A registered study indexed because it matched monitored longevity research terms. Registry status: Active Not Recruiting. Registration does not establish safety or effectiveness.

Plain-language guide

Five questions to ask about this record

What this is
A clinical study registration, not a result or recommendation.
Why it may matter
The registry currently reports Active Not Recruiting.
Evidence
Registered phase not reported study.
Main limitation
Registration does not prove that the intervention works, is safe, or is available to you.
What changed
Registry metadata was last updated December 31, 2025.
Where to verify
Open the primary registry below for eligibility, locations, contacts, and current status.
Registry ID
NCT07203196
Last registry update
December 31, 2025
Status
Active Not Recruiting
Phase
Phase not reported
Sponsor
Salk Institute for Biological Studies
Enrollment
16
Countries
United States
Match confidence
100%
Source feed
ClinicalTrials.gov
Automated source synopsis

A registered study indexed because it matched monitored longevity research terms. Registry status: Active Not Recruiting. Registration does not establish safety or effectiveness.

Evidence snapshot

What the source actually supports

Evidence stage
Phase not reported
Study design
NA · SINGLE GROUP · TREATMENT · NONE
Evidence population
Human clinical study registration
Participants
16
Population
ALL · 50 Years to 80 Years
Duration
2025-10-22 to 2026-04-01
Intervention
Circadian Rhythm Optimization
Comparator
Not reported
Outcomes measured
HbA1c (%) — Baseline and 90 days; Grip Strength — Baseline and 90 days; Isometric Knee Strength — Baseline and 90 days; VO2 Max — Baseline and 90 days; Time to 85% of Age Predicted Maximal Heart Rate — Baseline and 90 days; Flanker Inhibitory and Control and Attention Test (Fully-Corrected T-score) — Baseline and 90 days; Dimensional Change Card Sort (Fully-Corrected T-score) — Baseline and 90 days; Pattern Comparison Processing Speed Test (Fully-Corrected T-score) — Baseline and 90 days; Picture Sequence Memory test (Fully-Corrected T-score) — Baseline and 90 days; Trail Making Test — Baseline and 90 days; Glucagon (pg/mL) — Baseline and 90 days; Leptin (ng/mL) — Baseline and 90 days; IL-1α (pg/mL) — Baseline and 90 days; IL-1β (pg/mL) — Baseline and 90 days; IL-2 (pg/mL) — Baseline and 90 days; IL-3 (pg/mL) — Baseline and 90 days; IL-4 (pg/mL) — Baseline and 90 days; IL-5 (pg/mL) — Baseline and 90 days; IL-6 (pg/mL) — Baseline and 90 days; IL-7 (pg/mL) — Baseline and 90 days
Reported result
No reusable finding-level result is available in this record.

Main limitationThis is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.

Safety and approvalEligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians. Trial registration is not regulatory approval and does not establish that an intervention is available.

Source supportStructured registry protocol metadata; no finding-level conclusion is generated.

Trial stage · Phase not reportedA trial phase describes development stage; it does not establish a positive result.
Phase 1Phase 2Phase 3Phase 4

Registration and recruitment status do not establish safety, efficacy, or regulatory approval.

Why this record appears here · 100% topic match

The title, summary, or source keywords matched one or more topics followed by immortal.life. A higher percentage means a stronger topic match; it does not rate safety, effectiveness, or study quality.

  • Sleep · 100%Title contains controlled term: circadian. Abstract contains controlled term: sleep, circadian. Source terminology contains: circadian. Title supplies longevity context: rejuvenation. Study type is explicitly identified as INTERVENTIONAL.

Automated source check 100% · update recency 85%. These figures help sort records; they are not medical ratings.